6-oxo-5-(1,1,2,2-tetrafluoroethylthio)-4-trifluoromethyl-3-oxatricyclo[6.2.1.0^2,7]undeca-4,9-diene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃
• 英文名称: 6-oxo-5-(1,1,2,2-tetrafluoroethylthio)-4-trifluoromethyl-3-oxatricyclo[6.2.1.0^2,7]undeca-4,9-diene
• 英文别名: (1R,2R,7S,8S)-5-(1,1,2,2-tetrafluoroethylsulfanyl)-4-(trifluoromethyl)-3-oxatricyclo[6.2.1.02,7]undeca-4,9-dien-6-one
• 化学式: C₁₃H₉F₇O₂S
• 分子量: 362.268
• InChiKey: JXTBELKWIIAVQB-BYPJNBLXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  ethyl 4,4,4-trifluoro-3-oxo-2-(1,1,2,2-tetrafluoroethylthio)butanoate 在 phosphorus pentoxide 作用下， 反应 20.0h， 生成 6-oxo-5-(1,1,2,2-tetrafluoroethylthio)-4-trifluoromethyl-3-oxatricyclo[6.2.1.0^2,7]undeca-4,9-diene
  参考文献：
  名称：

  摘要：

  A procedure was developed for the synthesis of polyfluoroalkylthiotrifluoroacetylketenes, and their reactions with nucleophilic reagents were studied. The resulting compounds were demonstrated to act as heterodienes in reactions with unsaturated compounds.

  DOI：

  10.1023/a:1026033527150

文献信息

• ——
  作者：R. N. Serdyuk、A. Yu. Sizov、A. F. Ermolov

  DOI：10.1023/a:1026033527150

  日期：——

  A procedure was developed for the synthesis of polyfluoroalkylthiotrifluoroacetylketenes, and their reactions with nucleophilic reagents were studied. The resulting compounds were demonstrated to act as heterodienes in reactions with unsaturated compounds.