(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid;(9Z,12Z)-octadeca-9,12-dienoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid;(9Z,12Z)-octadeca-9,12-dienoic acid
• 化学式: C40H64O4
• 分子量: 608.9
• InChiKey: ZAOVDWTWACMPCF-FNFGQXKTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.43
• 重原子数：
  44
• 可旋转键数：
  28
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• ANDROGRAPHIS PANICULATA COMPOSITIONS AND METHODS FOR TREATMENT OF ADDICTIONS
  申请人：Omeros Corporation

  公开号：EP2866817A2

  公开（公告）日：2015-05-06
• Andrographis Paniculata Compositions and Methods for Treatment of Addictions
  申请人：Omeros Corporation

  公开号：US20140072662A1

  公开（公告）日：2014-03-13

  Methods and compositions for the treatment or prevention of addictions and impulse control disorders using Andrographis paniculata , active substances contained therein and extracts thereof, alone or in combination with other therapeutic agents. The methods and compositions of the invention are useful in the treatment or prevention of addiction to substances, including alcohol, nicotine, marijuana, opioid agonists cocaine, and amphetamines, as well as impulse control disorders, including pathological gambling and pathological overeating.
• [EN] ANDROGRAPHIS PANICULATA COMPOSITIONS AND METHODS FOR TREATMENT OF ADDICTIONS<br/>[FR] COMPOSITIONS D'ANDROGRAPHIS PANICULATA ET PROCÉDÉS DE TRAITEMENT D'ADDICTIONS
  申请人：OMEROS CORP

  公开号：WO2014008351A2

  公开（公告）日：2014-01-09

  Methods and compositions for the treatment or prevention of addictions and impulse control disorders using Andrographis paniculata, active substances contained therein and extracts thereof, alone or in combination with other therapeutic agents. The methods and compositions of the invention are useful in the treatment or prevention of addiction to substances, including alcohol, nicotine, marijuana, opioid agonists cocaine, and amphetamines, as well as impulse control disorders, including pathological gambling and pathological overeating.