(2S)-2-amino-3-[4-(2-diazohydrazinyl)phenyl]propanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-amino-3-[4-(2-diazohydrazinyl)phenyl]propanoic acid
• 化学式: C9H11N5O2
• 分子量: 221.22
• InChiKey: MPCIIPJGBAWIQM-QMMMGPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  89.7
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• MODIFIED FC PROTEINS COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES OF THE SAME, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE
  申请人：Sutro Biopharma, Inc.

  公开号：EP2863955B1

  公开（公告）日：2016-11-23
• [EN] MODIFIED AMINO ACIDS COMPRISING AN AZIDO GROUP<br/>[FR] ACIDES AMINÉS MODIFIÉS COMPRENANT UN GROUPE AZIDO
  申请人：SUTRO BIOPHARMA INC

  公开号：WO2014036492A1

  公开（公告）日：2014-03-06

  Provided herein are modified amino acids comprising an azido group, polypeptides, antibodies and conjugates comprising the modified amino acids, and methods of producing the polypeptides, antibodies and conjugates comprising the modified amino acids. The polypeptides, antibodies and conjugates are useful in methods of treatment and prevention, methods of detection and methods of diagnosis.
• [EN] ANTIBODIES COMPRISING MULTIPLE SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE<br/>[FR] ANTICORPS COMPRENANT PLUSIEURS RÉSIDUS D'ACIDES AMINÉS NON NATURELS SITE-SPÉCIFIQUES, DES PROCÉDÉS PERMETTANT LEUR PRÉPARATION ET LEURS MÉTHODES D'UTILISATION
  申请人：SUTRO BIOPHARMA INC

  公开号：WO2015006555A2

  公开（公告）日：2015-01-15

  Provided herein are antibodies comprising multiple non-natural amino acid residues at site-specific positions, compositions comprising the antibodies, methods of their production and methods of their use. The antibodies are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.