2-[5-(4-Morpholin-4-ylphenyl)pyridin-2-yl]acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 2-[5-(4-Morpholin-4-ylphenyl)pyridin-2-yl]acetamide
• 英文别名: 2-[5-(4-morpholin-4-ylphenyl)pyridin-2-yl]acetamide
• 化学式: C₁₇H₁₉N₃O₂
• 分子量: 297.35
• InChiKey: BMAKNNQBJSTCLX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  68.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] N-(3-FLUOROBENZYL)-2-(5-(4-MORPHOLINOPHENYL)PYRIDIN-2-YL) ACETAMIDE AS PROTEIN|TYROSINE KINASE MODULATORS<br/>[FR] N-(3-FLUOROBENZYL)-2-(5-(4-MORPHOLINOPHENYL)PYRIDIN-2-YL) ACÉTAMIDE UTILISÉ EN TANT QUE MODULATEURS DE LA PROTÉINE TYROSINE KINASE
  申请人：KINEX PHARMACEUTICALS LLC

  公开号：WO2014036426A1

  公开（公告）日：2014-03-06

  The invention relates to compounds and methods for modulating one or more components of a kinase cascade. The invention also relats to substantially pure compound 1 and substantially pure compound 1 salt (e.g., compound 1 hydrochloride salt and compound 1 benzenesulfonate salt). The invention further relates to methods of preparing substantially pure compound 1 and compound 1 salts.