2-Phenyl-2-piperidin-2-ylhexadecanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Phenyl-2-piperidin-2-ylhexadecanoic acid
• 英文别名: 2-phenyl-2-piperidin-2-ylhexadecanoic acid
• 化学式: C₂₇H₄₅NO₂
• 分子量: 415.7
• InChiKey: KIWIJWDYKITQDB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  30
• 可旋转键数：
  16
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Abuse-proofed dosage forms
  申请人：GRUENENTHAL GMBH

  公开号：US20140080915A1

  公开（公告）日：2014-03-20

  The invention relates to a form of administration which is secured against misuse and which is thermoformed without extrusion, comprising at least one synthetic or natural polymer having a resistance to breaking of at least 500 N in addition to one or several active ingredients with a misuse potential and, optionally physiologically compatible auxiliary substances. The invention also relates to a method for the production thereof.