Oct-6-yne-1,2,3-triol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Oct-6-yne-1,2,3-triol
• 英文别名: oct-6-yne-1,2,3-triol
• 化学式: C₈H₁₄O₃
• 分子量: 158.19
• InChiKey: SMSYVUYDPBIISM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• ANTISPASMODIC 1,2-DIOLS AND 1,2,3-TRIOLS
  申请人：Prima Innovations LLC

  公开号：EP2854782A1

  公开（公告）日：2015-04-08
• [EN] ANTISPASMODIC 1,2-DIOLS AND 1,2,3-TRIOLS<br/>[FR] 1,2-DIOLS ET 1,2,3-TRIOLS ANTISPASMODIQUES
  申请人：PRIMA INNOVATIONS LLC

  公开号：WO2013181084A1

  公开（公告）日：2013-12-05

  The present invention is directed to pharmaceutical compositions comprising antispasmodic C4-C8aliphatic-l,2-diols and C4-C8aliphatic-l,2,3-triols and their use to relieve the spasms associated with pain. These agents may be administered topically or orally and may be combined with anti-inflammatory agents such as a non-steroidal anti-inflammatory drug or a corticosteroid. Administration of the C4-C8aliphatic-l,2-diols and C4-C8aliphatic-l,2,3-triols with vitamin D3 is indicated for conditions such as bone loss, weight gain and autoimmune diseases such as lupus and rheumatoid arthritis.