The present disclosure relates to polymers which contain a hydrophobic and hydrophilic segment which is sensitive to pH. In some aspects, the polymers form a micelle which is sensitive to pH and results in a change in fluorescence based upon the particular pH. In some aspects, the disclosure also provides methods of using the polymers for the imaging of cellular or extracellular environment or delivering a drug.
本公开涉及含有对pH敏感的疏
水和亲
水片段的聚合物。在某些方面,这些聚合物形成对pH敏感的胶束,并基于特定pH值导致荧光变化。在某些方面,本公开还提供了使用这些聚合物进行细胞或细胞外环境成像或药物传递的方法。