2-[Bis(2-aminoethyl)amino]ethylcarbamic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[Bis(2-aminoethyl)amino]ethylcarbamic acid
• 英文别名: 2-[bis(2-aminoethyl)amino]ethylcarbamic acid
• 化学式: C₇H₁₈N₄O₂
• 分子量: 190.24
• InChiKey: KPWQTOOKFDMWMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.5
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  105
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• [EN] THIOHYDROXYPYRIDINE CHELATES<br/>[FR] CHÉLATES DE THIOHYDROXYPYRIDINE
  申请人：LUMIPHORE INC

  公开号：WO2022087317A1

  公开（公告）日：2022-04-28

  There is a provided metal ion chelating agents capable of stably binding soft Lewis acid metal ions, metal ion chelates based on these chelating agents, and methods of using the compounds of the invention in diagnostic and therapeutics methods. Also provided are methods of sequestering soft Lewis acid metal ions. Exemplary soft Lewis acid metal ions are radionuclides.

  提供了一种金属离子螯合剂，能够稳定地结合软路易斯酸金属离子，基于这些螯合剂的金属离子螯合物，并且提供了使用该发明中化合物进行诊断和治疗方法的方法。还提供了隔离软路易斯酸金属离子的方法。软路易斯酸金属离子的示例是放射性核素。
• ULTRABRIGHT LUMINESCENT LANTHANIDE NANOPARTICLES COMPRISING TERBIUM, WITH LONGER EXCITED-STATE LIFETIME
  申请人：Université de Strasbourg

  公开号：EP3591024B1

  公开（公告）日：2021-01-13
• [EN] MACROCYCLES<br/>[FR] MACROCYCLES
  申请人：UNIV CALIFORNIA

  公开号：WO2013187971A2

  公开（公告）日：2013-12-19

  The invention provides macrocycles useful in chelating metal ions, particularly radionuclides, to provide metal ion complexes. The invention also provides methods of using the compounds and complexes of the invention, such as in therapeutic and diagnostic applications.
• [EN] ULTRABRIGHT LUMINESCENT LANTHANIDE NANOPARTICLES COMPRISING TERBIUM, WITH LONGER EXCITED-STATE LIFETIME<br/>[FR] NANOPARTICULES DE LANTHANIDE LUMINESCENTES À TRÈS HAUTE LUMINOSITÉ COMPRENANT DU TERBIUM, PRÉSENTANT UNE DURÉE DE VIE DE L'ÉTAT EXCITÉ PLUS LONGUE
  申请人：UNIV STRASBOURG

  公开号：WO2020007966A1

  公开（公告）日：2020-01-09

  The invention provides luminescent lanthanide nanoparticles having simultaneously an improved brightness and an increased lifetime of the excited-state. These nanoparticles comprise terbium ions and ions of a second lanthanide, preferentially europium, and are coated with molecules of chromophore ligand bonded to the surface of the nanoparticle. The ligand is an organic molecule comprising at least one chromophore radical of formula (I) or of formula (II): wherein R is selected from H, CN group or COOH group. The phosphorescence excited-state lifetime is improved by energy transfer from surface terbium ions to core ions of the second lanthanide. The nanoparticle may further comprise a carrier molecule of analytical interest covalently attached to at least one ligand molecule.