2-(2-nitropyrrol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: 2-(2-nitropyrrol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide
• 化学式: C9H8F5N3O3
• 分子量: 301.17
• InChiKey: OSPKTMHAEOKDHO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  79.8
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• [EN] COMPOUNDS AND METHODS FOR SELECTIVE IMAGING AND/OR ABLATION<br/>[FR] COMPOSÉS ET PROCÉDÉS POUR L'IMAGERIE ET/OU L'ABLATION SÉLECTIVES
  申请人：AUCKLAND UNISERVICES LTD

  公开号：WO2014007650A1

  公开（公告）日：2014-01-09

  The invention relates generally to compounds and methods for imaging and/or selective ablation of nitroreductase-expressing cells and/or biological agents. More particularly, although not exclusively, the invention provides compounds that are selectively metabolised by bacterial nitroreductases and are substantially insensitive to metabolism under oxic or hypoxic conditions by human nitroreductase enzymes.

  本发明涉及一般化合物和方法，用于成像和/或选择性消融硝基还原酶表达细胞和/或生物制剂。更具体地，尽管不是唯一的，本发明提供了一些选择性被细菌硝基还原酶代谢并且在氧化或缺氧条件下对人体硝基还原酶酶不敏感的化合物。
• Compounds And Methods For Selective Imaging And/Or Ablation
  申请人：Auckland Uniservices Limited

  公开号：US20150010474A1

  公开（公告）日：2015-01-08

  The invention relates generally to compounds and methods for imaging and/or selective ablation of nitroreductase-expressing cells and/or biological agents. More particularly, although not exclusively, the invention provides compounds that are selectively metabolised by bacterial nitroreductases and are substantially insensitive to metabolism under oxic or hypoxic conditions by human nitroreductase enzymes.

  本发明涉及化合物和方法，用于成像和/或选择性消融硝基还原酶表达的细胞和/或生物制剂。更具体地说，虽然不仅限于此，本发明提供的化合物被细菌硝基还原酶选择性代谢，且在人类硝基还原酶酶下氧化或缺氧条件下代谢相对不敏感。
• Surfactant composition
  申请人：RHODIA OPERATIONS

  公开号：US10196556B2

  公开（公告）日：2019-02-05

  The invention provides a synergistic surfactant composition comprising: (a) from 5 to 95 wt % of a first surfactant which is selected from derivatives of alkyl polyglucosides and mixtures thereof; and (b) from 5 to 95 wt % of a second surfactant which is selected from: amphoteric surfactants, cationic surfactants, anionic surfactants, non-ionic surfactants, and mixtures thereof. This surfactant composition may be used to generate foam that is used for unloading a liquid from a hydrocarbon reservoir. It may be that the liquid unloading of foam generated using the surfactant composition is greater than that of foam generated from the first and second surfactants when they are foamed individually.

  本发明提供了一种增效表面活性剂组合物，该组合物包括：(a) 5 至 95 wt % 的第一种表面活性剂，该表面活性剂选自烷基多糖苷的衍生物及其混合物；(b) 5 至 95 wt % 的第二种表面活性剂，该表面活性剂选自两性表面活性剂、阳离子表面活性剂、阴离子表面活性剂、非离子表面活性剂及其混合物。这种表面活性剂组合物可用来产生泡沫，用于从碳氢化合物储层中卸载液体。使用该表面活性剂组合物产生的泡沫的液体卸载能力可能大于第一种和第二种表面活性剂单独发泡产生的泡沫。
• Corrosion inhibitors
  申请人：RHODIA OPERATIONS

  公开号：US10550482B2

  公开（公告）日：2020-02-04

  The invention provides the use of a surfactant as a corrosion inhibitor, wherein the surfactant is selected from derivatives of alkyl polyglucosides and derivatives of terpene alkoxylates, and mixtures thereof, provided that the derivatives are not sulfosuccinates. Also provided is a method of preventing or reducing corrosion of a metal component that is in contact with, or will be in contact with, an aqueous fluid, wherein the method comprises providing a surfactant and applying the surfactant to the metal component or adding the surfactant to the aqueous fluid that is in contact with, or will be in contact with, the metal component, wherein the surfactant is selected from derivatives of alkyl polyglucosides and derivatives of terpene alkoxylates, and mixtures thereof, provided that the derivatives are not sulfosuccinates.

  本发明提供了表面活性剂作为腐蚀抑制剂的用途，其中表面活性剂选自烷基多葡糖苷的衍生物和萜烯烷氧基化物的衍生物，以及它们的混合物，条件是这些衍生物不是磺基琥珀酸酯。还提供了一种防止或减少与水性流体接触或将与水性流体接触的金属部件腐蚀的方法，其中该方法包括提供一种表面活性剂，并将该表面活性剂涂抹到金属部件上，或将该表面活性剂添加到与金属部件接触或将与金属部件接触的水性流体中，其中该表面活性剂选自烷基多糖苷的衍生物和萜烯烷氧基化物的衍生物及其混合物，前提是该衍生物不是磺基琥珀酸酯。
• COMPOUNDS AND METHODS FOR SELECTIVE IMAGING AND/OR ABLATION
  申请人：Auckland Uniservices Limited

  公开号：EP2793871A1

  公开（公告）日：2014-10-29