5H-pyrrolo[1,2-a]imidazole-3-carboxamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 5H-pyrrolo[1,2-a]imidazole-3-carboxamide
• 化学式: C₇H₇N₃O
• 分子量: 149.15
• InChiKey: QQNQWOWCCWTBLR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  60.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• 5,5-HETEROAROMATIC ANTI-INFECTIVE COMPOUNDS
  申请人：UNIVERSITY OF NOTRE DAME DU LAC

  公开号：US20150210715A1

  公开（公告）日：2015-07-30

  The invention provides a series of 5,5-heteroaromatic compounds, syntheses thereof, compositions thereof, and methods of using such compounds and compositions. Various embodiments provide methods of killing and/or inhibiting the growth of M. tuberculosis and/or M. avium , and methods of treating, preventing, and/or ameliorating M. tuberculosis and/or M. avium infections in a subject. In various embodiments, the 5,5-heteroaromatic compound is N-(4-(4-chlorophenoxy)benzyl)-2,6-dimethylimidazo[2,1-b]thiazole-5-carboxamide.

  该发明提供了一系列5,5-杂环芳烃化合物，其合成方法，组合物以及使用这些化合物和组合物的方法。各种实施方式提供了杀灭和/或抑制结核分枝杆菌和/或分枝杆菌的生长的方法，以及治疗、预防和/或改善受试者体内结核分枝杆菌和/或分枝杆菌感染的方法。在各种实施方式中，5,5-杂环芳烃化合物为N-(4-(4-氯苯氧基)苄基)-2,6-二甲基咪唑[2,1-b]噻唑-5-羧酰胺。
• COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE
  申请人：Bayer CropScience AG

  公开号：EP2854535A1

  公开（公告）日：2015-04-08
• US9605002B2
  申请人：——

  公开号：US9605002B2

  公开（公告）日：2017-03-28
• [EN] COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE<br/>[FR] COMPOSITIONS COMPRENANT UN AGENT DE LUTTE BIOLOGIQUE ET UN INSECTICIDE
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2013178662A1

  公开（公告）日：2013-12-05

  The present invention relates to a composition comprising at least one bioiogical control agent selected from the group consisting of Bacillus chitinosporus AQ746 (NRRL Accession No. B-21618), Bacillus mycoides AQ726 (NRRL Accession No. B-21664), Bacillus pumilus (NRRL Accession No. B-30087), Bacillus pumilus AQ717 (NRRL Accession No. B-21662), Bacillus sp. AQ175 (ATCC Accession No. 55608), Bacillus sp. AQ177 (ATCC Accession No. 55609). Bacillus sp. AQ178 (ATCC Accession No. 53522), Bacillus subtllis AQ743 (NRRL Accession No, B-21665), Bacillus subtills AQ713 (NRRL Accession No, B-21661 ), Bacillus subtllis AQ153 (ATCC Accession No. 55614), Bacillus thurlnglensis BD#32 (NRRL Accession No. B-21530), Bacillus thurlnglensis AQ52 (NRRL Accession No. B-21619), Musccdor albus 620 (NRRL Accession No. 30547), Muscodor roseus A3-5 (NRRL Accession No. 30548), Rhodococcus glcberulus AQ71 9 (NRRL Accession No, B-21663), Streptomyces gaibus (NRRL Accession No. 30232), Sfreptomyces sp. (NRRL Accession No, B-30145), Bacillus thurlnglensis subspec. kurstaki BMP 123, Bacillus subtllis AQ30002 (NRRL Accession No. B-50421 ), and Bacillus subtllis AQ 30004 (NRRL Accession No. B-50455) and/or a mutant of these strains having all the identifying characteristics of the respective strain, and/or a metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopafhogens and at least one insecticide selected from the group consisting of juvenile hormone mimics, in a synergisticaliy effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.