[(2S)-1-(carboxyamino)-5-(dimethylamino)-7-methyl-5-(2-methylpropyl)octan-2-yl]carbamic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: [(2S)-1-(carboxyamino)-5-(dimethylamino)-7-methyl-5-(2-methylpropyl)octan-2-yl]carbamic acid
• 化学式: C₁₇H₃₅N₃O₄
• 分子量: 345.5
• InChiKey: VWJYLMWUSBROMN-AWEZNQCLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  24
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  102
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS
  申请人：THE TEXAS A&M UNIVERSITY SYSTEM

  公开号：US20150165429A1

  公开（公告）日：2015-06-18

  In some embodiments, the present disclosure pertains to a compound, comprising a transition metal complex having the formula Φ-[M(x,y)-L 1 (w,v)-L 2 (t,u)-L 3 ] p+ An − m Z − p — m . In an embodiment of the present disclosure Φ may be A. In another embodiment Φ may be Δ. In some embodiments of the present disclosure, M is a transition metal. In a related embodiment, p is an integer corresponding to the oxidation state of M. In some embodiments of the present disclosure, each of x, y, w, v, t, and u independently comprise R. In other embodiments, each of x, y, w, v, t, and u independently comprise S. In an embodiment of the present disclosure, each of L 1 , L 2 , and L 3 independently is a ligand comprising a substituted diamine. In some embodiments, An″ comprises a lipophilic anion, where m is from 1 to 3, and where Z − comprises an optional second anion.

  在某些实施例中，本公开涉及一种化合物，包括具有公式Φ-[M（x，y）-L1（w，v）-L2（t，u）-L3]p+An−mZ−p—m的过渡金属配合物。在本公开的某种实施例中，Φ可以是A。在另一种实施例中，Φ可以是Δ。在本公开的某些实施例中，M是一种过渡金属。在相关实施例中，p是与M的氧化态相对应的整数。在本公开的某些实施例中，x，y，w，v，t和u中的每个都独立地包括R。在其他实施例中，x，y，w，v，t和u中的每个都独立地包括S。在本公开的某种实施例中，L1、L2和L3中的每个都独立地是包含取代二胺的配体。在某些实施例中，An″包括一个亲脂性阴离子，其中m从1到3，而Z−包括一个可选的第二个阴离子。
• Transition metal complexes for enantioselective catalysis of carbon-carbon, carbon-heteroatom, and carbon-hydrogen bond forming reactions
  申请人：Lewis Kyle G.

  公开号：US10189871B2

  公开（公告）日：2019-01-29

  In some embodiments, the present disclosure pertains to a compound, comprising a transition metal complex having the formula Φ-[M (x,y)-L1 (w,v)-L2 (t,u)-L3]p+An−mZ−p−m. In an embodiment of the present disclosure Φ may be Λ. In another embodiment Φ may be Δ. In some embodiments of the present disclosure, M is a transition metal. In a related embodiment, p is an integer corresponding to the oxidation state of M. In some embodiments of the present disclosure, each of x, y, w, v, t, and u independently comprise R. In other embodiments, each of x, y, w, v, t, and u independently comprise S. In an embodiment of the present disclosure, each of L1, L2, and L3 independently is a ligand comprising a substituted diamine. In some embodiments, An− comprises a lipophilic anion, where m is from 1 to 3, and where Z− comprises an optional second anion.

  在一些实施方案中，本公开涉及一种化合物，该化合物包含具有式 Φ-[M (x,y)-L1 (w,v)-L2 (t,u)-L3]p+An-mZ-p-m 的过渡金属配合物。在本公开的一个实施方案中，Φ 可以是Λ。在本公开的一些实施方案中，M 是过渡金属。在本公开的一些实施方案中，x、y、w、v、t和u中的每一个独立地包括R。在其它实施方案中，x、y、w、v、t和u中的每一个独立地包括S。在本公开的一个实施方案中，L1、L2和L3中的每一个独立地是包括取代二胺的配体。在一些实施方案中，An-包括亲脂阴离子，其中m为1至3，Z-包括任选的第二阴离子。
• US9446393B2
  申请人：——

  公开号：US9446393B2

  公开（公告）日：2016-09-20
• [EN] TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS<br/>[FR] COMPLEXES DE MÉTAL DE TRANSITION POUR LA CATALYSE ÉNANTIOSÉLECTIVE DE RÉACTIONS DE FORMATION DE LIAISONS CARBONE-CARBONE, CARBONE-HÉTÉROATOME ET CARBONE-HYDROGÈNE
  申请人：TEXAS A & M UNIV SYS

  公开号：WO2014018978A2

  公开（公告）日：2014-01-30

  In some embodiments, the present disclosure pertains to a compound, comprising a transition metal complex having the formula Φ-[Μ (x,y)-L1 (w,v)-L2 (t,u)-L3]p+An-mZ-p_m. In an embodiment of the present disclosure Φ may be A. In another embodiment Φ may be Δ. In some embodiments of the present disclosure, M is a transition metal. In a related embodiment, p is an integer corresponding to the oxidation state of M. In some embodiments of the present disclosure, each of x, y, w, v, t, and u independently comprise R. In other embodiments, each of x, y, w, v, t, and u independently comprise S. In an embodiment of the present disclosure, each of L1, L2, and L3 independently is a ligand comprising a substituted diamine. In some embodiments, An" comprises a lipophilic anion, where m is from 1 to 3, and where Z- comprises an optional second anion.