(4Z,7Z,11E,13E,15Z,17R,19Z)-10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (4Z,7Z,11E,13E,15Z,17R,19Z)-10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid
• 化学式: C₂₂H₃₂O₄
• 分子量: 360.5
• InChiKey: CRDZYJSQHCXHEG-NLICRBOHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  26
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Topical formulations and uses thereof
  申请人：OCULAR TECHNOLOGIES SARL

  公开号：US10441630B2

  公开（公告）日：2019-10-15

  Provided herein include formulations for topical administration, such as ophthalmic formulations, and methods of using such formulations. In some aspects and embodiments the formulations may include a polyoxyl lipid or fatty acid, and or a polyalkoxylated alcohol and may include nanomicelles. Also include methods of treating or preventing diseases or conditions, such as ocular diseases or conditions.

  本文提供了用于局部用药的制剂，如眼科制剂，以及使用此类制剂的方法。在某些方面和实施方案中，制剂可包括聚氧乙烯脂质或脂肪酸，以及或聚烷氧基化醇，并可包括纳米细胞。还包括治疗或预防疾病或病症（如眼部疾病或病症）的方法。
• US20140275247A1
  申请人：——

  公开号：US20140275247A1

  公开（公告）日：2014-09-18
• TOPICAL FORMULATIONS AND USES THEREOF
  申请人：OCULAR TECHNOLOGIES SARL

  公开号：US20150165048A1

  公开（公告）日：2015-06-18

  Provided herein include formulations for topical administration, such as ophthalmic formulations, and methods of using such formulations. In some aspects and embodiments the formulations may include a polyoxyl lipid or fatty acid, and or a polyalkoxylated alcohol and may include nanomicelles. Also include methods of treating or preventing diseases or conditions, such as ocular diseases or conditions.
• US8673881B2
  申请人：——

  公开号：US8673881B2

  公开（公告）日：2014-03-18
• US9315447B2
  申请人：——

  公开号：US9315447B2

  公开（公告）日：2016-04-19