3-[3-[(2Z,5Z,8Z,10E,14Z)-heptadeca-2,5,8,10,14-pentaenyl]oxiran-2-yl]propanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-[3-[(2Z,5Z,8Z,10E,14Z)-heptadeca-2,5,8,10,14-pentaenyl]oxiran-2-yl]propanoic acid
• 化学式: C₂₂H₃₂O₃
• 分子量: 344.5
• InChiKey: PKUABYPAPMIGCW-UOIJAYFBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  25
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] OPHTHALMIC FORMULATION OF POLYOXYL LIPID OR POLYOXYL FATTY ACID AND TREATMENT OF OCULAR CONDITIONS<br/>[FR] FORMULATION OPHTALMIQUE D'ACIDE GRAS OU LIPIDIQUE DE POLYOXYLE, ET TRAITEMENT DE PATHOLOGIES OCULAIRES
  申请人：MITRA ASHIM K

  公开号：WO2014032026A1

  公开（公告）日：2014-02-27

  Provided herein include formulations for topical administration, such as ophthalmic formulations, and methods of using such formulations. In some aspects and embodiments the formulations may include a polyoxyl lipid or fatty acid, and or a polyalkoxylated alcohol and may include nanomicelles. Also include methods of treating or preventing diseases or conditions, such as ocular diseases or conditions.
• [EN] TOPICAL FORMULATIONS AND USES THEREOF<br/>[FR] FORMULATIONS TOPIQUES ET UTILISATIONS ASSOCIÉES
  申请人：OCULAR TECH SARL

  公开号：WO2017083167A1

  公开（公告）日：2017-05-18

  Provided herein include formulations for topical administration, such as ophthalmic formulations, and methods of using such formulations. In some aspects and embodiments the formulations may include a polyoxyl lipid or fatty acid, and/or a polyalkoxylated alcohol and may include nanomicelles. Also include methods of treating or preventing diseases or conditions, such as ocular diseases or conditions.