(5S,6E,8E,10R)-13-(3,4-dichlorophenyl)-5,10-dihydroxytrideca-6,8-dien-12-ynoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (5S,6E,8E,10R)-13-(3,4-dichlorophenyl)-5,10-dihydroxytrideca-6,8-dien-12-ynoic acid
• 化学式: C₁₉H₂₀Cl₂O₄
• 分子量: 383.3
• InChiKey: RSSXIWNYBWHIBT-RINYAVKVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  25
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• [EN] OPHTHALMIC FORMULATION OF POLYOXYL LIPID OR POLYOXYL FATTY ACID AND TREATMENT OF OCULAR CONDITIONS<br/>[FR] FORMULATION OPHTALMIQUE D'ACIDE GRAS OU LIPIDIQUE DE POLYOXYLE, ET TRAITEMENT DE PATHOLOGIES OCULAIRES
  申请人：MITRA ASHIM K

  公开号：WO2014032026A1

  公开（公告）日：2014-02-27

  Provided herein include formulations for topical administration, such as ophthalmic formulations, and methods of using such formulations. In some aspects and embodiments the formulations may include a polyoxyl lipid or fatty acid, and or a polyalkoxylated alcohol and may include nanomicelles. Also include methods of treating or preventing diseases or conditions, such as ocular diseases or conditions.