6-[2,5-dioxo-3-[(2R)-3-sulfanyl-2-(trifluoromethylsulfonylamino)propanoyl]pyrrolidin-1-yl]-N-methylhexanamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-[2,5-dioxo-3-[(2R)-3-sulfanyl-2-(trifluoromethylsulfonylamino)propanoyl]pyrrolidin-1-yl]-N-methylhexanamide
• 化学式: C₁₅H₂₂F₃N₃O₆S₂
• 分子量: 461.5
• InChiKey: TULLXUWCUMFZHF-AXDSSHIGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  29
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  139
• 氢给体数：
  3
• 氢受体数：
  11

文献信息

• [EN] PEPTIDE-DENDRIMER CONJUGATES AND USES THEREOF<br/>[FR] CONJUGUÉS PEPTIDES-DENDRIMÈRES ET LEURS UTILISATIONS
  申请人：ANGIOCHEM INC

  公开号：WO2014026283A1

  公开（公告）日：2014-02-20

  The invention relates to dendrimers conjugated to multiple targeting peptides and one or more therapeutic, diagnostic, or imaging agents for delivery of such agents across the blood-brain barrier and into certain cell types including, cells expressing the LRP-1 receptor. Also described are methods of making compounds that comprise dendrimers conjugated to targeting peptides and therapeutic, diagnostic, or imaging agents.