(4S)-4-[[2-(diaminomethylideneamino)acetyl]-hydroxyamino]-5-[[(2R,3S,5R)-5-(2,4-dioxo-1H-pyrimidin-5-yl)-3-hydroxyoxolan-2-yl]methylamino]-5-oxopentanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (4S)-4-[[2-(diaminomethylideneamino)acetyl]-hydroxyamino]-5-[[(2R,3S,5R)-5-(2,4-dioxo-1H-pyrimidin-5-yl)-3-hydroxyoxolan-2-yl]methylamino]-5-oxopentanoic acid
• 化学式: C₁₇H₂₅N₇O₉
• 分子量: 471.4
• InChiKey: BHUIDNSHBRJDJY-UKKRHICBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.3
• 重原子数：
  33
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  259
• 氢给体数：
  8
• 氢受体数：
  10

文献信息

• [EN] PSEUDOURIDIMYCIN (PUM) AND ITS DERIVATES<br/>[FR] PSEUDO-URIDIMYCINE (PUM) ET SES DÉRIVÉS
  申请人：NEW ANTI INFECTIVES CONSORTIUM S C A R L

  公开号：WO2014024013A1

  公开（公告）日：2014-02-13

  The present invention relates to novel compounds of formula (I) and pharmaceutically acceptable salts thereof, a process for the preparation thereof, as well as pharmaceutical compositions containing them and the use thereof as drugs, particularly for the treatment of infectious diseases.