(2S,4R)-N-[(1S)-2-chloro-1-[(3R,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S,4R)-N-[(1S)-2-chloro-1-[(3R,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
• 化学式: C₁₈H₃₃ClN₂O₅S
• 分子量: 425.0
• InChiKey: KDLRVYVGXIQJDK-FKZSIOLLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  128
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• CLINDAMYCIN PHOSPHATE, SALICYLIC ACID AND TEA TREE OIL COMBINATIONS
  申请人：IMUNEKS FARM MAC SANAYI VE TICARET A.S.

  公开号：US20150352165A1

  公开（公告）日：2015-12-10

  The present invention relates to the topical compositions comprising clindamycin phosphate, salicylic acid and tea tree oil; to the preparation methods thereof; and to the use thereof in the treatment of skin infections and acne vulgaris accompanied by inflammatory lesions.
• [EN] CLINDAMYCIN PHOSPHATE, SALICYLIC ACID AND TEA TREE OIL COMBINATIONS<br/>[FR] COMBINAISONS DE PHOSPHATE DE CLINDAMYCINE, D'ACIDE SALICYLIQUE ET D'HUILE DE THÉIER
  申请人：IMUNEKS FARMA MAC SANAYI VE TICARET A S

  公开号：WO2014042604A1

  公开（公告）日：2014-03-20

  The present invention relates to the topical compositions comprising clindamycin phosphate, salicylic acid and tea tree oil; to the preparation methods thereof; and to the use thereof in the treatment of skin infections and acne vulgaris accompanied by inflammatory lesions.