[2-[[2,3-Bis[(2-bromo-2-methylpropanoyl)oxy]-2-[(2-bromo-2-methylpropanoyl)oxymethyl]propoxy]methyl]-3-(2-bromo-2-methylpropanoyl)oxy-2-[(2-bromo-2-methylpropanoyl)oxymethyl]propyl] 2-bromo-2-methylpropanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: [2-[[2,3-Bis[(2-bromo-2-methylpropanoyl)oxy]-2-[(2-bromo-2-methylpropanoyl)oxymethyl]propoxy]methyl]-3-(2-bromo-2-methylpropanoyl)oxy-2-[(2-bromo-2-methylpropanoyl)oxymethyl]propyl] 2-bromo-2-methylpropanoate
• 英文别名: [2-[[2,3-bis[(2-bromo-2-methylpropanoyl)oxy]-2-[(2-bromo-2-methylpropanoyl)oxymethyl]propoxy]methyl]-3-(2-bromo-2-methylpropanoyl)oxy-2-[(2-bromo-2-methylpropanoyl)oxymethyl]propyl] 2-bromo-2-methylpropanoate
• 化学式: C₃₃H₅₀Br₆O₁₃
• 分子量: 1134.2
• InChiKey: IMCYPEXEEXQIMS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  52
• 可旋转键数：
  27
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  167
• 氢给体数：
  0
• 氢受体数：
  13

文献信息

• US9518207B2
  申请人：——

  公开号：US9518207B2

  公开（公告）日：2016-12-13
• [EN] METHOD OF INHIBITING CATHEPSIN ACTIVITY<br/>[FR] PROCEDE D'INHIBITION DE L'ACTIVITE DE CATHEPSINE
  申请人：SCHERING CORP

  公开号：WO2006113942A2

  公开（公告）日：2006-10-26

  [EN] The present invention provides methods of inhibiting cathepsin activity in a subject in need thereof comprising administering to said subject an effective amount of at least one compound of various formulae (e.g., formula I-XXVI) disclosed herein. The present invention also provides methods of treatment of various diseases utilizing the foregoing compounds.
  [FR] L'invention concerne des procédés d'inhibition de l'activité de la cathepsine chez un sujet le nécessitant qui consiste à administrer à ce sujet une quantité efficace d'au moins un composé de diverses formules (par exemple, formule I-XXVI). Cette invention concerne également des procédés de traitement de diverses maladies au moyen des composés susmentionnés.
• [EN] METHODS TO PREVENT FORMATION DAMAGE FROM FRICTION REDUCERS<br/>[FR] PROCÉDÉS POUR EMPÊCHER LA FORMATION DE DOMMAGE À PARTIR D'AGENTS RÉDUCTEURS DE FROTTEMENT
  申请人：HALLIBURTON ENERGY SERV INC

  公开号：WO2014004145A1

  公开（公告）日：2014-01-03

  A method of servicing a wellbore comprising placing a wellbore servicing fluid comprising a modified friction reducer into the wellbore. A modified friction reducer comprising a degradable polymer having functional degradable moieties, a polymer having a molecular weight of from about 5M to about 30M, a polymer having a PDI of from about 1.0 to about 2.5, a weakly crosslinked polymer, or combinations thereof.