2,9-dihydroxy-5,6-dithia-decanedioic acid | 33770-86-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,9-dihydroxy-5,6-dithia-decanedioic acid
• 英文别名: Bis-(3-carboxy-3-hydroxy-propyl)-disulfid；2,9-Dihydroxy-5,6-dithia-decandisaeure；4,4'-dithiobis (2-hydroxybutanoic acid)；4-[(3-Carboxy-3-hydroxypropyl)disulfanyl]-2-hydroxybutanoic acid
• CAS: 33770-86-4
• 化学式: C₈H₁₄O₆S₂
• 分子量: 270.328
• InChiKey: UOMIUEUBLBDUQG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  16
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  166
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  2-羟基-4-硫烷基丁酸 生成 2,9-dihydroxy-5,6-dithia-decanedioic acid 、 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Preparation of hydroxy mercapto butyric acids and derivatives thereof

  摘要：

  公开号：

  US02946818A1

文献信息

• Methods for treating of skin conditions with retinoid double conjugate compounds
  申请人：US COSMECEUTECHS LLC

  公开号：US10123960B2

  公开（公告）日：2018-11-13

  A double conjugate molecule made of a retinoid, an organic acid, particularly an a-hydroxy acid, and an alcohol or acyl group, is provided which is useful in treating skin conditions, particularly aging. The retinoid, organic acid, and alcohol/acyl group are preferably linked via ester bonds.

  提供一种由视黄醇、有机酸（特别是α-羟基酸）和醇或酰基组成的双共轭分子，可用于治疗皮肤状况，特别是衰老。视黄醇、有机酸和醇/酰基组最好通过酯键连接。
• RETINOID DOUBLE CONJUGATE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS FOR TREATING OF SKIN CONDITIONS
  申请人：US COSMECEUTECHS LLC

  公开号：US20160287507A1

  公开（公告）日：2016-10-06

  A double conjugate molecule made of a retinoid, an organic acid, particularly an α-hydroxy acid, and an alcohol or acyl group, is provided which is useful in treating skin conditions, particularly aging. The retinoid, organic acid, and alcohol/acyl group are preferably linked via ester bonds.
• US4363815A
  申请人：——

  公开号：US4363815A

  公开（公告）日：1982-12-14
• Preparation of hydroxy mercapto butyric acids and derivatives thereof
  申请人：MONSANTO CHEMICALS

  公开号：US02946818A1

  公开（公告）日：1960-07-26