1,4-Dioctoxy-1,4-dioxobutane-2-sulfonic acid;silver

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1,4-Dioctoxy-1,4-dioxobutane-2-sulfonic acid;silver
• 英文别名: 1,4-dioctoxy-1,4-dioxobutane-2-sulfonic acid;silver
• 化学式: C20H38AgO7S
• 分子量: 530.4
• InChiKey: AHKKAMCTCDIBES-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.44
• 重原子数：
  29
• 可旋转键数：
  20
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  115
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• [EN] COMPOSITIONS AND METHODS FOR MODULATING LIVER ENDOTHELIAL CELL FENESTRATIONS<br/>[FR] COMPOSITIONS ET MÉTHODES POUR MODULER LES FENESTRATIONS DE CELLULES ENDOTHÉLIALES HÉPATIQUES
  申请人：LECOUTEUR DAVID

  公开号：WO2019109124A1

  公开（公告）日：2019-06-13

  There is provided compositions and methods for modulating the fenestration porosity, fenestration frequency or fenestration diameter of liver endothelial cells. In particular compositions comprising conjugates of quantum dots and a therapeutic are used to modulate the fenestration porosity, frequency or diameter of liver endothelial cells.

  本发明提供了一种调节肝内皮细胞的小孔孔隙度、小孔频率或小孔直径的组合物和方法。具体而言，包含量子点和治疗剂的共轭物被用于调节肝内皮细胞的小孔孔隙度、频率或直径。
• Preparation method of near-infrared silver sulfide quantum dots
  申请人：SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS, CHINESE ACADEMY OF SCIENCES

  公开号：US10421901B2

  公开（公告）日：2019-09-24

  Provided is a preparation method of near-infrared silver sulfide quantum dots. The silver sulfide quantum dots have hydrophilic groups derived from a mercapto-containing hydrophilic reagent attached on the surface thereof, and the hydrophilic reagent is any one of mercaptoacetic acid, mercaptopropionic acid, cysteine, cysteamine, thioctic acid and ammonium mercaptoacetate or any combination thereof. The silver sulfide quantum dots have high fluorescence yield, good fluorescence stability, good biocompatibility and uniform sizes. The preparation method has moderate reaction conditions, simple operation, short production cycle, good reproducibility and is easy to control. The silver sulfide quantum dots can be used in the application of cellular imaging and biological tissue imaging.

  本发明提供了一种近红外硫化银量子点的制备方法。硫化银量子点表面附有由含巯基亲水试剂衍生的亲水基团，亲水试剂为巯基乙酸、巯基丙酸、半胱氨酸、半胱胺、硫辛酸和巯基乙酸铵中的任意一种或它们的任意组合。硫化银量子点具有荧光产率高、荧光稳定性好、生物相容性好、尺寸均匀等特点。该制备方法反应条件适中，操作简单，生产周期短，重现性好，易于控制。硫化银量子点可用于细胞成像和生物组织成像。
• PREPARATION METHOD FOR NEAR-INFRARED SILVER SULFIDE QUANTUM DOTS
  申请人：Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences

  公开号：EP2716733B1

  公开（公告）日：2016-10-26
• COMPOSITIONS AND METHODS FOR MODULATING LIVER ENDOTHELIAL CELL FENESTRATIONS
  申请人：Lecouteur, David

  公开号：EP3720506A1

  公开（公告）日：2020-10-14
• NEAR-INFRARED SILVER SULFIDE QUANTUM DOT, PREPARATION METHOD THEREFOR AND BIOLOGICAL APPLICATION THEREOF
  申请人：Wang Qiangbin

  公开号：US20140087409A1

  公开（公告）日：2014-03-27

  Provided are near-infrared silver sulfide quantum dots, a preparation method thereof and a biological application thereof. The silver sulfide quantum dots have hydrophilic groups derived from a mercapto-containing hydrophilic reagent attached on the surface thereof, and the hydrophilic reagent is any one of mercaptoacetic acid, mercaptopropionic acid, cysteine, cysteamine, thioctic acid and ammonium mercaptoacetate or any combination thereof. The silver sulfide quantum dots have high fluorescence yield, good fluorescence stability, good biocompatibility and uniform sizes. The preparation method has moderate reaction conditions, simple operation, short production cycle, good reproducibility and is easy to control. The silver sulfide quantum dots can be used in the application of cellular imaging and biological tissue imaging.