2-Amino-6-(2-azidoethylcarbamoyloxy)hexanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Amino-6-(2-azidoethylcarbamoyloxy)hexanoic acid
• 英文别名: 2-amino-6-(2-azidoethylcarbamoyloxy)hexanoic acid
• 化学式: C9H17N5O4
• 分子量: 259.26
• InChiKey: NWUGJXMBRWSRJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  18
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  116
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• CELL LINES
  申请人：MedImmune Limited

  公开号：EP2898085A1

  公开（公告）日：2015-07-29
• [EN] CELL LINES<br/>[FR] LIGNÉE CELLULAIRE
  申请人：ALLOZYNE INC

  公开号：WO2014044872A1

  公开（公告）日：2014-03-27

  There is provided inter alia a process for stabilizing a eukaryotic cell line which expresses PylRS and tRNAPyl and which is suitable for incorporation of a gene encoding a target protein containing one or more non-natural amino acids encoded by a nonsense codon which comprises culturing said cell line under conditions in which the adverse effect of tRNAPyl expression on cell viability and/or cell growth is reduced or eliminated.