Cyclohexyl 8-oxooctanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Cyclohexyl 8-oxooctanoate
• 英文别名: cyclohexyl 8-oxooctanoate
• 化学式: C₁₄H₂₄O₃
• 分子量: 240.34
• InChiKey: OFJPRFOWSMYEAI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  17
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• METHOD OF TREATING CANCER
  申请人：Intensity Therapeutics, Inc

  公开号：EP2897620A1

  公开（公告）日：2015-07-29
• [EN] METHOD OF TREATING CANCER<br/>[FR] PROCÉDÉ DE TRAITEMENT DU CANCER
  申请人：INTENSITY THERAPEUTIC

  公开号：WO2014046983A1

  公开（公告）日：2014-03-27

  The invention provides a method for treating cancer using a coadministration strategy that combines local codelivery of a therapeutic agent and an intracellular penetration enhancing agent, and optionally in further combination with local administration of an immunotherapeutic agent, such as a cancer vaccine or NKT agonist. The invention also provides a method for treating cancer using an intracellular penetration enhancing agent. The methods of the invention aim to substantially kill and/or destroy the target tumor cells, as well as those cancerous cells that have metastasized to other parts of the body.