Pentyl 2-hydroxy-2-methylpent-4-enoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Pentyl 2-hydroxy-2-methylpent-4-enoate
• 英文别名: pentyl 2-hydroxy-2-methylpent-4-enoate
• 化学式: C₁₁H₂₀O₃
• 分子量: 200.27
• InChiKey: BHNQDLDDMOMHGT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] LACTATE PRODUCTION PROCESS<br/>[FR] PROCÉDÉ DE PRODUCTION DE LACTATE
  申请人：PLAXICA LTD

  公开号：WO2014045036A1

  公开（公告）日：2014-03-27

  A process for producing a compound of formula (I) is provided. The process comprises reacting a mixture comprising a compound of formula (IIA) and a compound of formula (IIB) with an alkyl alcohol in the presence of a Candida antarctica lipase B enzyme to produce a product comprising the compound of formula (I) and the compound of formula (IIB); wherein R1 is C1 to C6 alkyl; and wherein R2 is H or C1 to C12 alkyl. Also provided are processes for the production of R-lactic acid, oligomeric R-lactic acid, R,R-lactide, poly-R-lactic acid, alkyl S-lactate, S-lactic acid, oligomeric S-lactic acid, S,S-lactide, poly S-lactic acid and stereocomplex polylactic acid.

  提供一种制备化合物(I)的方法。该方法包括在存在Candida antarctica脂肪酶B酶的情况下，通过反应含有化合物(IIA)和化合物(IIB)的混合物与烷基醇来制备含有化合物(I)和化合物(IIB)的产物；其中R1为C1至C6烷基；R2为H或C1至C12烷基。还提供了生产R-乳酸、寡聚R-乳酸、R,R-内酯、聚R-乳酸、烷基S-乳酸、S-乳酸、寡聚S-乳酸、S,S-内酯、聚S-乳酸和立体复合聚乳酸的方法。