20-[[(1S)-1-carboxypropyl]amino]-20-oxoicosanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 20-[[(1S)-1-carboxypropyl]amino]-20-oxoicosanoic acid
• 化学式: C₂₄H₄₅NO₅
• 分子量: 427.6
• InChiKey: YSTFOMRVIZVJKL-NRFANRHFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  30
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  104
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Polypeptides
  申请人：NOVO NORDISK A/S

  公开号：US20140087995A1

  公开（公告）日：2014-03-27

  The invention relates to polypeptides comprising an amino acid sequence which is an analogue of human amylin, pharmaceutical compositions comprising these polypeptides, and these polypeptides for use as medicaments.
• Novel N-Terminally Modified Insulin Derivatives
  申请人：Madsen Peter

  公开号：US20140315797A1

  公开（公告）日：2014-10-23

  The invention is related to novel N-terminally modified insulin derivatives, pharmaceutical compositions comprising such and methods of making such.
• MULTI-RECEPTOR AGONIST AND MEDICAL USE THEREOF
  申请人：JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD.

  公开号：US20220168396A1

  公开（公告）日：2022-06-02

  A series of pharmaceutical compositions containing polypeptide dual agonist compounds and pharmaceutically acceptable salts thereof, wherein same have dual agonist effects on a human glucagon-like peptide-1 (GLP-1) receptor and a human blood glucose-dependent insulinotropic polypeptide (GIP) receptor, and can be used for treating non-insulin-dependent diabetes, insulin-dependent diabetes, obesity and other related diseases.
• US9023789B2
  申请人：——

  公开号：US9023789B2

  公开（公告）日：2015-05-05
• US9029325B2
  申请人：——

  公开号：US9029325B2

  公开（公告）日：2015-05-12