2-[2-[2-[Carboxymethyl(methyl)amino]ethyl-methylamino]ethylamino]acetic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[2-[2-[Carboxymethyl(methyl)amino]ethyl-methylamino]ethylamino]acetic acid
• 英文别名: 2-[2-[2-[carboxymethyl(methyl)amino]ethyl-methylamino]ethylamino]acetic acid
• 化学式: C₁₀H₂₁N₃O₄
• 分子量: 247.29
• InChiKey: FNNSAXVBQHLSDS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.5
• 重原子数：
  17
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  93.1
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Single Wall Nanotube Constructs and Uses Thereof
  申请人：Scheinberg David A.

  公开号：US20140086831A1

  公开（公告）日：2014-03-27

  The present invention provides soluble single wall nanotube (SWNT) constructs functionalized with a plurality of a targeting moiety and a plurality of one or more payload molecules attached thereto. The targeting moiety and the payload molecules may be attached to the soluble SWNT via a DNA or other oligomer platform attached to the SWNT. These soluble SWNT constructs may comprise a radionuclide or contrast agent and as such are effective as diagnostic and therapeutic agents. Methods provided herein are to diagnosing or locating a cancer, treating a cancer, eliciting an immune response against a cancer or delivering an anticancer drug in situ via an enzymatic nanofactory using the soluble SWNT constructs.