Bis[2-[bis(carboxymethyl)amino]ethyl]-(carboxymethyl)azanium;acetate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Bis[2-[bis(carboxymethyl)amino]ethyl]-(carboxymethyl)azanium;acetate
• 英文别名: bis[2-[bis(carboxymethyl)amino]ethyl]-(carboxymethyl)azanium;acetate
• 化学式: C16H27N3O12
• 分子量: 453.4
• InChiKey: LSGXEJLGNPXYOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.35
• 重原子数：
  31
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  238
• 氢给体数：
  6
• 氢受体数：
  14

文献信息

• PROCESS FOR THE PREPARATION OF MACROCYCLIC POLYAZACARBOXYLATE LIGANDS AND CHELATES
  申请人：Guerbet

  公开号：EP2920156B9

  公开（公告）日：2017-04-19
• ASSESSMENT OF CANCER SUSCEPTIBILITY TO MOLECULAR TARGETED THERAPY BY USE OF RECOMBINANT PEPTIDES
  申请人：Hallahan Dennis E.

  公开号：US20100135905A1

  公开（公告）日：2010-06-03

  A method for assessing cancer susceptibility to molecular targeted therapy. Also provided are methods for in vivo panning of diverse molecules for isolation of targeting ligands that specifically bind an apoptotic cell associated with a responding tumor, targeting ligands identified by the panning methods, and diagnostic and imaging uses therefor.
• US9315474B2
  申请人：——

  公开号：US9315474B2

  公开（公告）日：2016-04-19
• US9777022B2
  申请人：——

  公开号：US9777022B2

  公开（公告）日：2017-10-03
• [EN] ASSESSMENT OF CANCER SUSCEPTIBILITY TO MOLECULAR TARGETED THERAPY BY USE OF RECOMBINANT PEPTIDES<br/>[FR] EVALUATION DE LA RECEPTIVITE D'UN CANCER A UN TRAITEMENT A CIBLE MOLECULAIRE AU MOYEN DE PEPTIDES RECOMBINES
  申请人：UNIV VANDERBILT

  公开号：WO2006028993A2

  公开（公告）日：2006-03-16

  A method for assessing cancer susceptibility to molecular targeted therapy. Also provided are methods for in vivo panning of diverse molecules for isolation of targeting ligands that specifically bind an apoptotic cell associated with a responding tumor, targeting ligands identified by the panning methods, and diagnostic and imaging uses therefor.