(2S)-2-amino-5-(octadecanoylamino)-5-oxopentanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-amino-5-(octadecanoylamino)-5-oxopentanoic acid
• 化学式: C₂₃H₄₄N₂O₄
• 分子量: 412.6
• InChiKey: LXDXWEFXMFWHIK-FQEVSTJZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  29
• 可旋转键数：
  20
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  110
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• [EN] IMMUNOSTIMULATING AGENT<br/>[FR] AGENT IMMUNOSTIMULANT
  申请人：AJINOMOTO KK

  公开号：WO2017073797A1

  公开（公告）日：2017-05-04

  The present invention aims to provide an immunostimulating agent superior in an immunostimulatory effect, particularly a compound useful as a vaccine adjuvant, a pharmaceutical composition containing the compound, a vaccine containing the compound and an antigen. The present invention relates to an immunostimulating agent containing at least one kind of a compound represented by the formula (I) : wherein each symbol is as defined in the DESCRIPTION, or a salt thereof, or at least one kind of a compound represented by the formula (II) : wherein each symbol is as defined in the DESCRIPTION, or a salt thereof.

  本发明旨在提供一种免疫刺激剂，其在免疫刺激效果方面优越，特别是作为疫苗佐剂有用的化合物，含有该化合物的药物组合物，含有该化合物和抗原的疫苗。本发明涉及一种免疫刺激剂，其至少包含下式(I)所表示的一种化合物：其中每个符号如描述中所定义，或其盐，或至少包含下式(II)所表示的一种化合物：其中每个符号如描述中所定义，或其盐。
• EP2908845A1
  申请人：——

  公开号：EP2908845A1

  公开（公告）日：2015-08-26
• IMMUNOSTIMULATING AGENT
  申请人：AJINOMOTO CO., INC.

  公开号：EP3368508A1

  公开（公告）日：2018-09-05
• Fatty Acid Acylated Amino Acids for Growth Hormone Delivery
  申请人：Novo Nordisk Health Care AG

  公开号：US20150250882A1

  公开（公告）日：2015-09-10

  The present invention relates to growth hormone compositions comprising a fatty acid acylated amino acids (FA-aa's), which may be used in pharmaceutical compositions such as pharmaceutical compositions for oral administration of growth hormone.
• [EN] FATTY ACID ACYLATED AMINO ACIDS FOR GROWTH HORMONE DELIVERY<br/>[FR] ACIDES AMINÉS ACYLÉS PAR UN ACIDE GRAS POUR L'ADMINISTRATION D'HORMONE DE CROISSANCE
  申请人：NOVO NORDISK HEALTHCARE AG

  公开号：WO2014060512A1

  公开（公告）日：2014-04-24

  The present invention relates to growth hormone compositions comprising a fatty acid acylated amino acids (FA-aa's), which may be used in pharmaceutical compositions such as pharmaceutical compositions for oral administration of growth hormone.