2-(3-Ethylpent-1-en-3-yloxycarbonyl)-4-methylpent-4-enoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-(3-Ethylpent-1-en-3-yloxycarbonyl)-4-methylpent-4-enoic acid
• 英文别名: 2-(3-ethylpent-1-en-3-yloxycarbonyl)-4-methylpent-4-enoic acid
• 化学式: C₁₄H₂₂O₄
• 分子量: 254.32
• InChiKey: ZLDXHZOKUCBAKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE<br/>[FR] CATALYSEURS DE MÉTATHÈSE À BASE DE RUTHÉNIUM, PRÉCURSEURS POUR LEUR PRÉPARATION ET LEUR UTILISATION
  申请人：UMICORE AG & CO KG

  公开号：WO2014067767A1

  公开（公告）日：2014-05-08

  The invention is directed to ruthenium-based metathesis catalysts of the Grubbs-Hoveyda type. The new 2-aryloxy-substituted ruthenium catalysts described herein reveal rapid initiation behavior. Further, the corresponding styrene-based precursor compounds are disclosed. The catalysts are prepared in a cross-metathesis reaction starting from styrene-based precursors which can be prepared in a cost- effective manner. The new Grubbs-Hoveyda type catalysts are suitable to catalyze ring- closing metathesis (RCM), cross metathesis (CM) and ring- opening metathesis polymerization (ROMP). Low catalyst loadings are necessary to convert a wide range of substrates including more complex and critical substrates via metathesis reactions at low to moderate temperatures in high yields within short reaction times.

  该发明涉及格鲁布斯-霍维达类型的基于钌的转化催化剂。本文描述的新型2-芳氧基取代的钌催化剂展现出快速启动行为。此外，还披露了相应的基于苯乙烯的前体化合物。这些催化剂是通过从基于苯乙烯的前体化合物开始的交叉转化反应制备的，可以以成本有效的方式制备。新型的格鲁布斯-霍维达类型催化剂适用于催化环闭合转化（RCM）、交叉转化（CM）和环开启转化聚合（ROMP）。在低至中等温度下，只需使用较低的催化剂负载即可将广泛范围的底物转化为更复杂和关键底物，从而在短时间内高产率地进行转化反应。
• Ruthenium-based metathesis catalysts, precursors for their preparation and their use
  申请人：Umicore AG & Co. KG

  公开号：EP2725030A1

  公开（公告）日：2014-04-30

  The invention is directed to ruthenium-based metathesis catalysts of the Grubbs-Hoveyda type. The new 2-aryloxy-substituted ruthenium catalysts described herein reveal rapid initiation behavior. Further, the corresponding styrene-based precursor compounds are disclosed. The catalysts are prepared in a cross-metathesis reaction starting from styrene-based precursors which can be prepared in a cost-effective manner. The new Grubbs-Hoveyda type catalysts are suitable to catalyze ring-closing metathesis (RCM), cross metathesis (CM) and ring-opening metathesis polymerization (ROMP). Low catalyst loadings are necessary to convert a wide range of substrates including more complex and critical substrates via metathesis reactions at low to moderate temperatures in high yields within short reaction times.

  该发明涉及格鲁布斯-霍维达类型的基于钌的交换催化剂。本文描述的新型2-芳氧基取代的钌催化剂展现出快速的起始行为。此外，还披露了相应的基于苯乙烯的前体化合物。这些催化剂是通过从基于苯乙烯的前体物开始的交叉交换反应制备的，这种方法可以以成本效益的方式进行。新的格鲁布斯-霍维达类型催化剂适用于催化环闭合交换反应（RCM）、交叉交换反应（CM）和环开启交换聚合反应（ROMP）。在低至中温度下，通过交换反应以低催化剂负载量转化各种底物，包括更复杂和关键的底物，可以在短时间内高产率地完成。
• RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE
  申请人：UMICORE AG & CO. KG

  公开号：US20150266009A1

  公开（公告）日：2015-09-24

  The invention is directed to ruthenium-based metathesis catalysts of the Grubbs-Hoveyda type. The new 2-aryloxy-substituted ruthenium catalysts described herein reveal rapid initiation behavior. Further, the corresponding styrene-based precursor compounds are disclosed. The catalysts are prepared in a cross-metathesis reaction starting from styrene-based precursors which can be prepared in a cost-effective manner. The new Grubbs-Hoveyda type catalysts are suitable to catalyze ring-closing metathesis (RCM), cross metathesis (CM) and ring-opening metathesis polymerization (ROMP). Low catalyst loadings are necessary to convert a wide range of substrates including more complex and critical substrates via metathesis reactions at low to moderate temperatures in high yields within short reaction times.

  本发明涉及Grubbs-Hoveyda型基于钌的交换催化剂。本文所描述的新型2-芳氧基取代钌催化剂表现出快速启动行为。此外，还公开了相应的苯乙烯基前体化合物。这些催化剂是通过交叉交换反应从苯乙烯基前体制备而成，可以以经济的方式制备。新的Grubbs-Hoveyda型催化剂适用于催化环内交换反应（RCM）、交叉交换反应（CM）和开环交换聚合反应（ROMP）。在低至中等温度下，仅需较低的催化剂负荷即可在短时间内高产率地将广泛的底物，包括更复杂和关键的底物，通过交换反应转化。