(2S)-2-amino-5-oxo-5-pentoxypentanoic acid;(2S)-2-(dodecanoylamino)pentanedioic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-amino-5-oxo-5-pentoxypentanoic acid;(2S)-2-(dodecanoylamino)pentanedioic acid
• 化学式: C27H50N2O9
• 分子量: 546.7
• InChiKey: TYKRIZOHLUYSMN-QHVORSOKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.25
• 重原子数：
  38
• 可旋转键数：
  24
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  193
• 氢给体数：
  5
• 氢受体数：
  10

文献信息

• Topical wash composition for use in acne patients
  申请人：Galderma S.A.

  公开号：US10688117B2

  公开（公告）日：2020-06-23

  Wash compositions for topical application are described. The compositions can be stable and well tolerated. Also described, are methods of using such compositions as cosmetic or pharmaceutical products. For example, the compositions can be used for cleansing the skin, preferably of acne patients, without compromising the skin barrier or resulting in over-compensation of sebum production. A topical wash composition is also described that can include: a) at least one surfactant; b) a zinc salt of gluconic acid; and c) a salt or derivative of glycyrrhizic acid or of glycyrrhetinic acid.

  描述了用于局部应用的洗涤组合物。这些组合物具有稳定性和良好的耐受性。此外，还介绍了将这种组合物用作化妆品或医药产品的方法。例如，这种组合物可用于清洁皮肤，最好是清洁痤疮患者的皮肤，而不会损害皮肤屏障或导致皮脂分泌过度。还描述了一种局部清洗组合物，它可以包括：a) 至少一种表面活性剂；b) 葡萄糖酸的锌盐；c) 甘草酸或甘草次酸的盐或衍生物。
• TOPICAL WASH COMPOSITION FOR USE IN ACNE PATIENTS
  申请人：Galderma S.A.

  公开号：US20140121176A1

  公开（公告）日：2014-05-01

  Wash compositions for topical application are described. The compositions can be stable and well tolerated. Also described, are methods of using such compositions as cosmetic or pharmaceutical products. For example, the compositions can be used for cleansing the skin, preferably of acne patients, without compromising the skin barrier or resulting in over-compensation of sebum production. A topical wash composition is also described that can include: a) at least one surfactant; b) a zinc salt of gluconic acid; and c) a salt or derivative of glycyrrhizic acid or of glycyrrhetinic acid.