(2S)-3-hexadecanoyloxypyrrolidine-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-3-hexadecanoyloxypyrrolidine-2-carboxylic acid
• 化学式: C₂₁H₃₉NO₄
• 分子量: 369.5
• InChiKey: WHOTZYOPLRYZQN-IJHRGXPZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  26
• 可旋转键数：
  17
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  75.6
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Composition and method of treating skin conditions
  申请人：Clark Stephen W.

  公开号：US10130573B1

  公开（公告）日：2018-11-20

  The present invention is a composition and method of treatment for skin disorders, conditions, and severe skin dryness in general through topical systematic and periodic application of a formulation that generally may include salicylic acid, glycolic acid, urea, dimethyl isosorbide, ethoxydiglycol, barrier repair agents, anti-irritants, humectants, and also has an acidic pH formulation.

  本发明是一种组合物和方法，通过局部系统性和定期施用一般可包括水杨酸、乙醇酸、尿素、二甲基异山梨醇、乙氧基二甘醇、屏障修复剂、抗刺激剂、保湿剂和酸性 pH 值配方的制剂，治疗一般皮肤疾病、状况和严重皮肤干燥。
• US9399009B1
  申请人：——

  公开号：US9399009B1

  公开（公告）日：2016-07-26
• [EN] LOW TOXICITY TOPICAL ACTIVE AGENT DELIVERY SYSTEM<br/>[FR] SYSTÈME D'ADMINISTRATION D'AGENT ACTIF TOPIQUE À FAIBLE TOXICITÉ
  申请人：KULESZA JOHN E

  公开号：WO2014066225A1

  公开（公告）日：2014-05-01

  An active agent delivery composition is provided that allows topical delivery of active agents including vitamin A and its derivatives. A volatile vehicle serves as a coupler for an active agent and an organosiloxane carrier so as to allow full solubilization of active agents not normally miscible in silicones and providing a non-irritating, targeted evaporating composition.