(E)-5-hydroxy-2-methyl-3-(2-oxopyrrolidin-1-yl)pent-2-enoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-5-hydroxy-2-methyl-3-(2-oxopyrrolidin-1-yl)pent-2-enoic acid
• 化学式: C₁₀H₁₅NO₄
• 分子量: 213.23
• InChiKey: FMUIXGHTTHPRJU-BQYQJAHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  77.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Personal care composition for a keratin substrate comprising conditioning and/or styling polymer
  申请人：HERCULES INNCORPORATED

  公开号：US10064805B2

  公开（公告）日：2018-09-04

  A personal care conditioning and/or styling composition for a keratin substrate comprising: (A) at least one conditioning and/or styling ter/tetra polymer obtained by polymerizing: (i) about 50 wt. % to 97 wt. % of at least one cationic or pseudo-cationic monomer selected from the group consisting of diallyl dimethyl ammonium chloride (DADMAC), Hydroxyethyl-pyrrolidone-methacrylate (MO6), and/or Vinylpyrrolidone (VP); (ii) about 1 wt. % to 30 wt. % of at least one anionic monomer selected from the group consisting of (a) acrylic acid (AA), (b) acrylamido methylpropyl sulfonate (AMPS), and/or (c) sodium methyl allyl sulfonate (SMAS); and (iii) about 0.1 wt. % to 20 wt. % of at least one hydrophobic monomer selected from the group consisting of (a) polyoxyethylene (PEG)-18-behenylether-methacrylate (BEM) (b) Lauryl-ethoxylated-methacrylate (LEM), (c) stearyl acrylate (SA), (d) Streath-10-allyl-ether, and/or (e) Vinylcaprolactam (V-cap); and wherein said ter/tetra polymer has a cationic degree of substitution (Cat-DS) of greater than about 0.001 units, and wherein the cationic charge density is in the range of about 1 meq/g to about 6.5 meq/g; (B) at least one cosmetically acceptable excipient; and (C) optionally, at least one effective amount of personal care active ingredient. Also, disclosed is a process of preparing said ter/tetra polymer, and its method of use.

  一种用于角蛋白基质的个人护理调理和/或定型组合物，包括：(A) 至少一种调理和/或定型三/四元聚合物，该聚合物通过以下聚合反应获得：(i) 约 50 重量份至 97 重量份的至少一种阳离子或假阳离子单体，该单体选自由二烯丙基二甲基氯化铵 (DADMAC)、羟乙基吡咯烷酮-甲基丙烯酸酯 (MO6) 和/或乙烯基吡咯烷酮 (VP) 组成的组；(ii) 约 1 重量份至 30 重量份的至少一种阴离子单体，该单体选自由 (a) 丙烯酸 (AA)、(b) 丙烯酸酰胺甲基丙基磺酸盐 (AMPS) 组成的组% 至 30 wt. % 的至少一种阴离子单体，该单体选自 (a) 丙烯酸 (AA)、(b) 丙烯酸酰胺甲基丙基磺酸盐 (AMPS)，和/或 (c) 甲基烯丙基磺酸钠 (SMAS) 组成的组；以及 (iii) 约 0.1 wt.(a)聚氧乙烯（PEG）-18-苯醚甲基丙烯酸酯（BEM）；(b)月桂基乙氧基化甲基丙烯酸酯（LEM）；(c)硬脂基丙烯酸酯（SA）；(d)Streath-10-烯丙基醚；和/或(e)乙烯基己内酰胺（V-cap）；其中所述三元/四元聚合物的阳离子取代度 (Cat-DS) 大于约 0.001 个单位，其中阳离子电荷密度在约 1 meq/g 至约 6.5 meq/g 的范围内；(B) 至少一种化妆品上可接受的赋形剂；以及 (C) 可选地，至少一种有效量的个人护理活性成分。此外，还公开了制备所述三/四元聚合物的工艺及其使用方法。
• Personal care composition for a keratin substrate comprising conditioning, color protecting and styling polymer
  申请人：ISP Investments LLC

  公开号：US10610480B2

  公开（公告）日：2020-04-07

  A personal care conditioning, color protecting and/or styling composition for a keratin substrate comprising: (A) at least one conditioning and/or styling ter/tetra polymer obtained from polymerizing: (i) about 0.1 wt. % to 99 wt. % of acrylamidopropyl trimethylammonium chloride (APTAC), a cationic monomer; (ii) about 0.1 wt. % to 30 wt. % of at least one anionic monomer selected from the group consisting of (a) acrylic acid (AA), (b) acrylamido methylpropyl sulfonate (AMPS), and/or (c) sodium methyl allyl sulfonate (SMAS); and (iii) about 0.1 wt. % to about 20 wt. % of methacryloylaminopropyl lauryl-dimethyl ammonium chloride (MAPLDMAC), a hydrophobically modified cationic monomer; (B) at least one cosmetically acceptable excipient; and (C) optionally, at least one effective amount of personal care active ingredient.

  一种用于角蛋白基质的个人护理调理、护色和/或定型组合物，包括： (A) 至少一种调理和/或定型三/四元聚合物，由以下物质聚合而成：(i) 约 0.1 重量 % 至 99 重量 % 的丙烯酰胺丙基三甲基氯化铵 (APTAC)，一种阳离子单体；(ii) 约 0.1 重量 % 至 30 重量 % 的至少一种阴离子单体，选自由丙烯酸 (AA)、(b) 丙烯酸酰胺甲基丙基磺酸盐 (AMPS) 和/或 (c) 丙烯酸酰胺甲基丙基磺酸钠 (AMPS) 组成的组。(a) 丙烯酸 (AA)，(b) 丙烯酸酰胺基甲基丙基磺酸盐 (AMPS)，和/或 (c) 甲基烯丙基磺酸钠 (SMAS)；和 (iii) 约 0.1 重量 % 至约 20 重量 % 的甲基丙烯酰氨基甲烷，一种阴离子单体； (iv) 约 0.1 重量 % 至约 30 重量 % 的甲基丙烯酰氨基甲烷。%的甲基丙烯酰氨基丙基月桂基二甲基氯化铵（MAPLDMAC），一种疏水改性阳离子单体；(B) 至少一种化妆品可接受的赋形剂；以及 (C) 可选的，至少一种有效量的个人护理活性成分。
• Personal care compositions comprising copolymers of cationic monomers and acryloyl lactam based monomers, process for the same and method of use
  申请人：ISP INVESTMENTS LLC

  公开号：US10765617B2

  公开（公告）日：2020-09-08

  Disclosed herein is a personal care conditioning and/or styling composition for keratin substrate comprising: (A) at least one conditioning and/or styling copolymer obtained from polymerizing: (i) about 0.1 wt. % to 99.9 wt. % of at least one cationic or pseudo-cationic monomer selected from the group consisting of acrylamidopropyl trimethylammonium chloride (APT AC) and/or diallyl dimethyl ammonium chloride (DADMAC); and (ii) about 0.1 wt. % to 99.9 wt. % of at least one monomer comprising at least one functionalized or unfunctionalized acryloyl moiety and at least one lactam moiety; (B) at least one cosmetically acceptable excipient; and (C) optionally, at least one effective amount of personal care active ingredient. Also disclose is a process for preparing such composition and method of use thereof.

  本文公开了一种用于角蛋白基质的个人护理调理和/或定型组合物，该组合物包含：(A) 至少一种调理和/或定型共聚物，该共聚物由以下物质聚合而成：(i) 约 0.1 重量％至 99.9 重量％的至少一种阳离子或假阳离子单体，该单体选自由丙烯酰胺丙基三甲基氯化铵（APT AC）和/或二烯丙基二甲基氯化铵（DADMAC）组成的组；以及 (ii) 约 0.1重量％至99.9重量％的至少一种单体，该单体包含至少一个官能化或未官能化的丙烯酰基和至少一个内酰胺基；(B) 至少一种化妆品可接受的赋形剂；以及(C) 可选地，至少一种有效量的个人护理活性成分。还公开了制备这种组合物的工艺及其使用方法。
• Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof
  申请人：HERCULES LLC

  公开号：US11001751B2

  公开（公告）日：2021-05-11

  The invention provides polymers comprising repeating units derived from at least one monomer comprising at least one functionalized or unfunctionalized acryloyl moiety and at least one lactam moiety; at least one monomer comprising at least one sulfonic acid moiety or a salt thereof; and at least one crosslinker. The invention further provides various compositions comprising the polymers. The invention furthermore provides applications of these compositions in various industrial arts, particularly in oilfield operations such as drilling and cementing.

  本发明提供的聚合物包含由至少一种单体衍生的重复单元，该单体包含至少一个官能化或非官能化丙烯酰基和至少一个内酰胺基；至少一种单体包含至少一个磺酸基或其盐；以及至少一种交联剂。本发明进一步提供了包含这些聚合物的各种组合物。本发明还提供了这些组合物在各种工业技术中的应用，特别是在钻井和固井等油田作业中的应用。
• COMPOSITION COMPRISING CONDITIONING AND/OR STYLING POLYMER
  申请人：Hercules LLC

  公开号：EP2914239B1

  公开（公告）日：2020-04-29