benzylcycloheptylamine | 17630-30-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzylcycloheptylamine
• 英文别名: N-benzylcycloheptanamine
• CAS: 17630-30-7
• 化学式: C₁₄H₂₁N
• mdl: MFCD07408109
• 分子量: 203.327
• InChiKey: KARSJEQFQOBUHO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.571
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  环庚胺 、 苯甲醇 在 六氯环三磷腈 作用下， 以 1,2,4-三甲基苯 为溶剂， 反应 36.0h， 以91%的产率得到benzylcycloheptylamine
  参考文献：
  名称：

  通过基于非金属基酸基的协同催化作用，将胺与醇选择性地进行N-烷基化反应

  摘要：

  学会合作：通过TAPC促进的基于非金属的催化方法，报道了一种直接的胺与醇选择性地将胺与醇进行N-单-和二烷基化的方法（参见方案）。针对每种胺（1°和2°；芳族和脂肪族）和醇（1°，2°和3°；苄基和脂肪族），重点介绍了N-单烷基和二烷基化的选择性，底物范围和官能团耐受性） 成分。

  DOI：

  10.1002/chem.201102446

文献信息

• [EN] METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO<br/>[FR] PROCÉDÉS DE PRÉPARATION DE COMPOSÉS FLUOROALKYLE ARYLSULFINYLÉS ET COMPOSÉS FLUORÉS APPARENTÉS
  申请人：IM & T RES INC

  公开号：WO2010022001A1

  公开（公告）日：2010-02-25

  Novel preparative methods for fluoroalkyl arylsulfinyl compounds are disclosed. Fluorinated compounds as useful fluorinated compounds, intermediates, or builing blocks are disclosed. Useful applications of the fluoroalkyl arylsulfinyl compounds are shown.

  揭示了用于制备氟烷基芳基磺酰基化合物的新型制备方法。公开了氟化合物作为有用的氟化合物、中间体或构建块。展示了氟烷基芳基磺酰基化合物的有用应用。
• Synthesis and algicidal activity of new dichlorobenzylamine derivatives against harmful red tides
  作者：Dubok Choi、Sunjong Yu、Seung Ho Baek、Yoon-Ho Kang、Young-Cheol Chang、Hoon Cho

  DOI：10.1007/s12257-016-0175-8

  日期：2016.6

  In the present study, we synthesized 65 dichlorobenzylamine derivatives and investigated their algicidal activity against harmful red tides. The 3,4-dichlorobenzylamine derivatives showed relatively high activity against Cochlodinium polykrikoides, Heterosigma akashiwo, Chattonella marina, and Heterocapsa circularisquama, and the synthesized compounds 27, 28, 33, 34, 35, and 36 showed the highest algicidal activity after 24 h at 0.1 ~ 1.0 μM LC50 against the four harmful algae species. To verify the safety of the compounds, acute ecotoxicology tests using the water flea (Daphnia magna) and zebrafish (Danio rerio) were conducted, and the tests confirmed that compounds 33 and 34 were not harmful because the target organisms showed high survival rates at 15 μM. The results indicate that compounds 33 and 34 are suitable substances for use in controlling harmful algae species.

  在本研究中，我们合成了65种二氯苄胺衍生物，并研究了它们对有害赤潮的藻类灭杀活性。3,4-二氯苄胺衍生物对多刺菱形藻、赤潮藻、海洋Chattonella以及圆形裙藻显示出较高的活性，而合成的化合物27、28、33、34、35和36在0.1 ~ 1.0 μM LC50条件下，在24小时后对这四种有害藻类展现出最高的藻类灭杀活性。为了验证这些化合物的安全性，我们进行了使用水蚤（Daphnia magna）和斑马鱼（Danio rerio）的急性生态毒理学测试，结果表明化合物33和34并不有害，因为目标生物在15 μM浓度下显示出较高的生存率。这些结果表明化合物33和34适合作为控制有害藻类的物质。
• COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS
  申请人：CUREARTH, INC.

  公开号：US20180271091A1

  公开（公告）日：2018-09-27

  The present disclosure relates to a composition for the destruction of microalgae or mosses. The composition for the destruction of microalgae or mosses may suppress the growth and proliferation of microalgae when treated in moss cultivation facilities, marine microalgae cultivation facilities, areas in which green or red tide is occurring, or areas in which green or red tide is expected to occur, thereby preventing damage caused by the green or red tide.

  本公开涉及一种用于消灭微藻或苔藓的组合物。该用于消灭微藻或苔藓的组合物在苔藓培育设施、海洋微藻培育设施、发生绿潮或红潮的区域，或者预计会发生绿潮或红潮的区域中处理时，可以抑制微藻的生长和繁殖，从而预防绿潮或红潮造成的损害。
• Methods For Preparing Fluoroalkyl Arylsulfinyl Compounds And Fluorinated Compounds Thereto
  申请人：Umemoto Teruo

  公开号：US20110190511A1

  公开（公告）日：2011-08-04

  Novel preparative methods for fluoroalkyl arylsulfinyl compounds are disclosed. Fluorinated compounds as useful fluorinated compounds, intermediates, or builing blocks are disclosed. Useful applications of the fluoroalkyl arylsulfinyl compounds are shown.

  本发明揭示了一种用于制备氟烷基芳基亚磺酰化合物的新型制备方法。本发明还揭示了氟化合物作为有用的氟化合物、中间体或构建块。同时，本发明还展示了氟烷基芳基亚磺酰化合物的有用应用。
• Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto
  申请人：Umemoto Teruo

  公开号：US20100152463A1

  公开（公告）日：2010-06-17

  Novel preparative methods for fluoroalkyl arylsulfinyl compounds are disclosed. Fluorinated compounds as useful fluorinated compounds, intermediates, or building blocks are disclosed. Useful applications of the fluoroalkyl arylsulfinyl compounds are shown.

  本发明公开了用于制备氟烷基芳基磺酰基化合物的新型制备方法。本发明还公开了作为有用的氟化合物、中间体或构建块的氟化合物。本发明还展示了氟烷基芳基磺酰基化合物的有用应用。