2-[2-(carboxymethyl)hydrazinyl]acetic acid;(2S)-2,6-diaminohexanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[2-(carboxymethyl)hydrazinyl]acetic acid;(2S)-2,6-diaminohexanoic acid
• 化学式: C10H22N4O6
• 分子量: 294.31
• InChiKey: SJTLNWKBNRGDKX-JEDNCBNOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.22
• 重原子数：
  20
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  188
• 氢给体数：
  7
• 氢受体数：
  10

文献信息

• AFFINITY TAGS ABLE TO DETECT FRAMESHIFTS
  申请人：Syndecion, LLC

  公开号：US20140135472A1

  公开（公告）日：2014-05-15

  Described are polynucleotide sequences that encode peptide affinity tags with the surprising property that all of the possible out-of-frame peptide sequences are identical to each other, yet are distinct from the in-frame encoded peptide tag. The present invention includes peptide affinity tags incorporated in expressed proteins. Also described are ligands and antibodies that recognize the in-frame peptides and separate ligands or antibodies that recognize the out-of-frame peptides.