3-[(3S,9S,12S,15S,18S,26S,29S)-12-(2-amino-2-oxoethyl)-24-[(3R)-3-bromo-2-oxobutyl]-20-carbamoyl-9-(carboxymethyl)-3,18-bis[3-(diaminomethylideneamino)propyl]-15-[(4-hydroxyphenyl)methyl]-2,5,8,13,16,19,22,25,28-nonaoxo-21-thia-1,4,7,10,11,14,17,23,27-nonazabicyclo[27.3.0]dotriacontan-26-yl]propanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-[(3S,9S,12S,15S,18S,26S,29S)-12-(2-amino-2-oxoethyl)-24-[(3R)-3-bromo-2-oxobutyl]-20-carbamoyl-9-(carboxymethyl)-3,18-bis[3-(diaminomethylideneamino)propyl]-15-[(4-hydroxyphenyl)methyl]-2,5,8,13,16,19,22,25,28-nonaoxo-21-thia-1,4,7,10,11,14,17,23,27-nonazabicyclo[27.3.0]dotriacontan-26-yl]propanoic acid
• 化学式: C₄₉H₇₂BrN₁₇O₁₇S
• 分子量: 1283.2
• InChiKey: JSGFFUKTDXAQDC-CXDZPQAASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -9.5
• 重原子数：
  85
• 可旋转键数：
  21
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  605
• 氢给体数：
  17
• 氢受体数：
  22

文献信息

• BIOCOMPATIBLE AND BIODEGRADABLE GRADIENT LAYER SYSTEM FOR REGENERATIVE MEDICINE AND FOR TISSUE SUPPORT
  申请人：Steinberg Thorsten

  公开号：US20140112973A1

  公开（公告）日：2014-04-24

  The present invention is directed to a biocompatible and preferably biodegradable gradient layer system comprising at least one set of layers comprising a biocompatible and preferably biodegradable cross-linked polymer and at least one biocompatible and preferably biodegradable support layer, wherein a gradient is preferably formed with respect to the mechanical and/or physical properties of one or more layers of the at least one set of layers comprising a biocompatible and biodegradable cross-linked polymer and/or the at least one biocompatible and preferably biodegradable support layer. The at least one support layer preferably comprises a biocompatible and preferably biodegradable meltable polymer and/or a biocompatible and incorporable material. This biocompatible and preferably biodegradable gradient layer system may be used as a biomaterial for regenerative medicine, particularly as a wound dressing or for tissue support. The present invention also provides means utilizing said inventive gradient layer system and methods for producing same.
• US9937278B2
  申请人：——

  公开号：US9937278B2

  公开（公告）日：2018-04-10