2-(4-(tert-butyl)phenyl)-4-(thiophen-2-ylmethylene)oxazol-5(4H)-one

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-(4-(tert-butyl)phenyl)-4-(thiophen-2-ylmethylene)oxazol-5(4H)-one
• 英文别名: (4E)-2-(4-tert-butylphenyl)-4-(thiophen-2-ylmethylidene)-1,3-oxazol-5-one
• 化学式: C₁₈H₁₇NO₂S
• 分子量: 311.404
• InChiKey: YSYKRUMSZLHQRC-RVDMUPIBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  66.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• NOVEL COMPOUND AND METHOD FOR PREVENTING OR TREATING OF RESPIRATORY DISEASES COMPRISING THE SAME AS AN ACTIVE INGREDIENT
  申请人：YONSEI UNIVERSITY, UNIVERSITY - INDUSTRY FOUNDATION (UIF)

  公开号：US20220193041A1

  公开（公告）日：2022-06-23

  The present invention relates to a novel compound, and a composition for preventing or treating of respiratory disease comprising the novel compound, E- or Z-isomer thereof, optical isomer thereof, a mixture of two isomers thereof, precursor thereof, pharmaceutically acceptable salt thereof or solvate thereof as an active ingredient.