(1S,3R)-N-ethyl-3-(methylamino)cyclopentane-1-carboxamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (1S,3R)-N-ethyl-3-(methylamino)cyclopentane-1-carboxamide
• 化学式: C₉H₁₈N₂O
• 分子量: 170.25
• InChiKey: NGYVCDYZGVDWTN-JGVFFNPUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  41.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] 3-AMINOCYCLOPENTANE CARBOXAMIDE DERIVATIVES<br/>[FR] DÉRIVÉS DE 3-AMINOCYCLOPENTANE CARBOXAMIDE
  申请人：MERCK PATENT GMBH

  公开号：WO2014075754A1

  公开（公告）日：2014-05-22

  Compounds of the formula (I) in which R1, R4, R, X1, X2, X3, X4, q and W have the meanings indicated in Claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.

  式（I）中R1、R4、R、X1、X2、X3、X4、q和W的含义如权利要求1所示，是脂肪酸合成酶的抑制剂，可用于治疗癌症、心血管疾病、中枢神经系统损伤和不同形式的炎症等疾病。
• 3-AMINOCYCLOPENTANE CARBOXAMIDE DERIVATIVES
  申请人：MERCK PATENT GMBH

  公开号：US20160264517A1

  公开（公告）日：2016-09-15

  Compounds of the formula I in which R 1 , R 4 , R, X 1 , X 2 , X 3 , X 4 , q and W have the meanings indicated in Claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.

  式子I中，R1、R4、R、X1、X2、X3、X4、q和W的含义如权利要求书1所示，是脂肪酸合酶的抑制剂，可用于治疗癌症、心血管疾病、中枢神经系统损伤和不同形式的炎症等疾病。
• US9732032B2
  申请人：——

  公开号：US9732032B2

  公开（公告）日：2017-08-15