(5R,6S)-6-hydroxy-5-methylheptan-3-one

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (5R,6S)-6-hydroxy-5-methylheptan-3-one
• 化学式: C₈H₁₆O₂
• 分子量: 144.21
• InChiKey: VZPXZAOPDGPOMM-RQJHMYQMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• CYCLOSPORINE ANALOGUE MOLECULES MODIFIED AT AMINO ACID 1 AND 3
  申请人：Hegmans Alexander

  公开号：US20140142033A1

  公开（公告）日：2014-05-22

  Analogues of cyclosporin-A are disclosed comprising modifications of the substituents as the positions of amino acids 1 and 3, according to the following Formula. The disclosed compounds include compounds having affinity for cyclophilin, including cyclophilin-A, and reduced immunosuppressivity in comparison with cyclosporin-A and analogs thereof modified solely at position 1.
• US9200038B2
  申请人：——

  公开号：US9200038B2

  公开（公告）日：2015-12-01