1,3,5-tri-O-acetyl-2,4,6-tri-O-methylgalactitol

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,3,5-tri-O-acetyl-2,4,6-tri-O-methylgalactitol
• 英文别名: 2,4,6-tri-O-methyl-1,3,5-tri-O-acetylgalactitol；[(2S,3R,4S,5R)-3,5-diacetyloxy-2,4,6-trimethoxyhexyl] acetate
• 化学式: C₁₅H₂₆O₉
• 分子量: 350.366
• InChiKey: NVJZDJXSKJXLCB-LJISPDSOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  24
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  107
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  (2R,3R,5R,6R)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol 生成 1,3,5-tri-O-acetyl-2,4,6-tri-O-methylgalactitol
  参考文献：
  名称：

  SHEA, ELAINE M.;CARPITA, NICHOLAS C., J. CHROMATOGR., 445,(1988) N 2, 424-428

  摘要：

  DOI：

文献信息

• Structure of the Klebsiella type 10 capsular polysaccharide
  作者：Arun K. Sarkar、Nirmolendu Roy

  DOI：10.1016/s0008-6215(00)90300-8

  日期：1986.9

  The capsular polysaccharide from Klebsiella Type 10 was found to contain D-galactose, D-glucose, D-mannose, and D-glucuronic acid in the ratios 3:1:1:1. Acid hydrolysis of the polysaccharide gave one aldobiouronic acid, one aldotriouronic acid, one aldotetraouronic acid, and two neutral disaccharides the structures of which were established. The native and carboxyl-reduced polysaccharide have been subjected

  发现来自10型克雷伯氏菌的荚膜多糖以3∶1∶1∶1∶1的比例含有D-半乳糖，D-葡萄糖，D-甘露糖和D-葡萄糖醛酸。多糖的酸水解得到一种醛糖二糖醛酸，一种醛糖三糖醛酸，一种醛糖四糖醛酸和两种中性二糖，其结构已确定。天然和羧基还原的多糖已经适当地进行了甲基化分析和史密斯降解。用碱基对甲基化多糖的降解建立了葡糖糖醛酸残基之前的糖单元的身份。糖残基的端基异构构型通过用三氧化铬氧化乙酰化的天然和羧基还原的多糖来确定。根据这些研究，
• Structure of the capsular polysaccharide of klebsiella serotype k53
  作者：Guy G.S. Dutton、Marcel Paulin

  DOI：10.1016/s0008-6215(00)85195-2

  日期：1980.12

  Klebsiella serotype K53 is one of three strains belonging to the chemotype whose capsular polysaccharides consist of D-glucuronic acid, D-galactose, D-mannose, and L-rhamnose residues, and the structure of its polysaccharide was found to be of the "5 + 1 type" shown, of the same structural pattern as the capsule from Klebsiella K52 (Formula, see text). Nimmich has analyzed the capsular polysaccharide

  克雷伯菌血清型K53是属于化学型的三个菌株之一，其荚膜多糖由D-葡萄糖醛酸，D-半乳糖，D-甘露糖和L-鼠李糖残基组成，其多糖结构被发现为“ 5”。显示了“ +1型”，其结构与Klebsiella K52的胶囊相同（配方，见正文）。Nimmich分析了克雷伯氏菌K53的荚膜多糖，并表明它属于化学型，还包含K40和K80。作为我们对这些多糖的持续研究的一部分，我们现在报告克雷伯菌K53荚膜抗原的结构。目前尚不清楚K40和K80的结构。
• Structure of the capsular polysaccharide of klebsiella serotype k74
  作者：Guy G.S. Dutton、Marcel Paulin

  DOI：10.1016/s0008-6215(00)85196-4

  日期：1980.12

  The capsular polysaccharide of Klebsiella serotype K74 belongs to a chemogroup consisting of seven strains, of which four contain 1-carboxyethylidene groups (pyruvic acid acetals). The polysaccharide from K74 is demonstrated to be of the "3 + 2" type, and to be based on the repeating unit shown (Formula, see text). The capsular polysaccharide from Klebsiella K74 is composed of D-glucuronic acid, D-galactose

  血清型K74克雷伯氏菌的荚膜多糖属于化学基团，由七个菌株组成，其中四个菌株含有1-羧乙叉基（丙酮酸缩醛）。已证实来自K74的多糖为“ 3 + 2”型，并且基于所示的重复单元（式，见正文）。来自克雷伯氏菌K74的荚膜多糖由D-葡萄糖醛酸，D-半乳糖和D-甘露糖组成，该化学型包括总共七个菌株，其中四个具有1-羧乙叉基（丙酮酸缩醛）。在该化学组中，已经公开了血清型K20（参考文献3）和K21（参考文献4）的荚膜多糖的结构。
• ANTI-ALLERGIC AGENT
  申请人：Morishita Jintan Co., Ltd.

  公开号：EP2551283A1

  公开（公告）日：2013-01-30

  According to the present invention, an anti-allergic agent is provided which includes a polysaccharide comprising galactose, glucose and rhamnose as constituents, or includes a microorganism belonging to the genus Bifidobacterium and extracellularly producing the polysaccharide. The anti-allergic agent of the present invention can be used in oral compositions and compositions for external application, and is suitable for use in products such as food products, pharmaceutical products, and cosmetics.

  根据本发明，提供了一种抗过敏剂，它包括一种以半乳糖、葡萄糖和鼠李糖为成分的多糖，或包括一种属于双歧杆菌属并在细胞外产生该多糖的微生物。本发明的抗过敏剂可用于口服组合物和外用组合物，并适用于食品、药品和化妆品等产品。
• The structural elucidation of the capsular polysaccharide of Klebsiella K68
  作者：Guy G.S. Dutton、Haralambos Parolis、Lesley S. Parolis

  DOI：10.1016/s0008-6215(00)90305-7

  日期：1986.9

  The structure of the capsular polysaccharide isolated from Klebsiella K68 bacteria has been elucidated by both chemical and spectroscopic methods. The structure is of the "3 + 1" type, similar in pattern to the structures of the polysaccharides of Klebsiella K11 and K57, having a single branch point on the uronic acid. The polysaccharide is shown to consist of the following repeating unit: (Formula: see text).