4-[2-[2-[2-(3-Carboxypropanoylamino)ethoxy]ethoxy]ethylamino]-4-oxobutanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-[2-[2-[2-(3-Carboxypropanoylamino)ethoxy]ethoxy]ethylamino]-4-oxobutanoic acid
• 英文别名: 4-[2-[2-[2-(3-carboxypropanoylamino)ethoxy]ethoxy]ethylamino]-4-oxobutanoic acid
• 化学式: C₁₄H₂₄N₂O₈
• 分子量: 348.35
• InChiKey: MRURVGLSCKHLSO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  24
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  151
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• Cross-linked poly-E-lysine non-particulate support
  申请人：SPHERITECH LTD

  公开号：US10266652B2

  公开（公告）日：2019-04-23

  The invention provides a non-particulate cross-linked poly-ε-lysine polymer. The poly-ε-lysine and cross linker are linked by amide bonds and may the cross linker has at least two functional groups capable of reacting with an alpha carbon amine of poly-ε-lysine. The polymer is suitably insoluble in water and other solvents and is provided in macro form for example a sheet, article or fiber. The macro form polymer is useful in a wide range of applications including wound treatment, as a medical diagnostic comprising a particulate support and a functional material bound or retained by the support and solid phase synthesis of peptides, oligonucleotides, oligosaccharides, immobilisation of species, cell culturing and in chromatographic separation.

  本发明提供了一种无颗粒交联聚-ε-赖氨酸聚合物。聚-ε-赖氨酸和交联剂通过酰胺键连接，交联剂可能至少有两个官能团能与聚-ε-赖氨酸的α碳胺反应。这种聚合物不溶于水和其他溶剂，可制成片状、条状或纤维状。巨型聚合物的应用范围很广，包括伤口处理、作为医疗诊断，包括微粒支持物和被支持物结合或保留的功能材料，以及肽、寡核苷酸、寡糖的固相合成、物种固定、细胞培养和色谱分离。
• CROSS-LINKED POLY-E-LYSINE PARTICLES
  申请人：Wellings Donald

  公开号：US20140154737A1

  公开（公告）日：2014-06-05

  The invention provides a cross-linked poly-ε-lysine polymer. The poly-ε-lysine and cross linker are linked by amide bonds and may the cross linker has at least two functional groups capable of reacting with an alpha carbon amine of poly-ε-lysine. The polymer is suitably insoluble in water and other solvents and is provided in particulate form. The invention provides a particulate support comprising the cross-linked poly-ε-lysine polymer and the polymer may provide the particle itself or be coated on a particle for example silica. The polymer is useful in a wide range of applications including wound treatment, as a medical diagnostic comprising a particulate support and a functional material bound or retained by the support and solid phase synthesis of peptides, oligonucleotides, oligosaccharides, immobilisation of species, cell culturing and in chromatographic separation.
• CROSS-LINKED POLY-E-LYSINE NON-PARTICULATE SUPPORT
  申请人：Wellings Donald

  公开号：US20140142198A1

  公开（公告）日：2014-05-22

  The invention provides a non-particulate cross-linked poly-ε-lysine polymer. The poly-ε-lysine and cross linker are linked by amide bonds and may the cross linker has at least two functional groups capable of reacting with an alpha carbon amine of poly-ε-lysine. The polymer is suitably insoluble in water and other solvents and is provided in macro form for example a sheet, article or fibre. The macro form polymer is useful in a wide range of applications including wound treatment, as a medical diagnostic comprising a particulate support and a functional material bound or retained by the support and solid phase synthesis of peptides, oligonucleotides, oligosaccharides, immobilisation of species, cell culturing and in chromatographic separation.
• Cross-Linked Poly-E-Lysine Non-Particulate Support
  申请人：SPHERITECH LTD

  公开号：US20190023844A1

  公开（公告）日：2019-01-24

  The invention provides a non-particulate cross-linked poly-ε-lysine polymer. The poly-ε-lysine and cross linker are linked by amide bonds and may the cross linker has at least two functional groups capable of reacting with an alpha carbon amine of poly-ε-lysine. The polymer is suitably insoluble in water and other solvents and is provided in macro form for example a sheet, article or fibre. The macro form polymer is useful in a wide range of applications including wound treatment, as a medical diagnostic comprising a particulate support and a functional material bound or retained by the support and solid phase synthesis of peptides, oligonucleotides, oligosaccharides, immobilisation of species, cell culturing and in chromatographic separation.
• US9938378B2
  申请人：——

  公开号：US9938378B2

  公开（公告）日：2018-04-10