Bis(2-hydroxypropanoyl) propanedioate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Bis(2-hydroxypropanoyl) propanedioate
• 英文别名: bis(2-hydroxypropanoyl) propanedioate
• 化学式: C₉H₁₂O₈
• 分子量: 248.19
• InChiKey: RICJBCSJQILEPV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  127
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL
  申请人：STATEGICS, INC.

  公开号：US20150307498A1

  公开（公告）日：2015-10-29

  Disclosed herein are erythropoietin-mimetic compounds of Formula I, which modulate the survival, function, or differentiation of, for example, kidney cells, neurons, erythroid cells, or other erythropoietin-responsive cells. The present invention also relates to compounds and methods that preferentially modulate cells expressing the tissue-protective erythropoietin receptor. The compounds of the invention are useful in preventing and treating diseases, such as anemia, organ injury, and diseases of the central nervous system, and as an adjunct to cellular treatments, such as stem cell therapies.

  本发明公开了式I的类似促红细胞生成素化合物，其调节例如肾细胞、神经元、红细胞或其他对促红细胞生成素敏感的细胞的存活、功能或分化。本发明还涉及优先调节表达组织保护性促红细胞生成素受体的细胞的化合物和方法。本发明的化合物对预防和治疗疾病，例如贫血、器官损伤和中枢神经系统疾病，以及作为细胞治疗的辅助剂，例如干细胞治疗，是有用的。
• Automatic dishwashing composition
  申请人：Reckitt Benckiser (Brands) Limited

  公开号：US10815451B2

  公开（公告）日：2020-10-27

  The present invention relates to an improved detergent composition for use in the protection of non-metallic inorganic materials such as glassware in automatic ware washing machines.

  本发明涉及一种用于保护自动器皿清洗机中的非金属无机材料（如玻璃器皿）的改良洗涤剂组合物。
• MACHINE CLEANING COMPOSITION
  申请人：Reckitt Benckiser (Brands) Limited

  公开号：EP3068856A1

  公开（公告）日：2016-09-21
• AUTOMATIC DISHWASHING COMPOSITION
  申请人：Reckitt Benckiser (Brands) Limited

  公开号：EP3149142A1

  公开（公告）日：2017-04-05
• Machine Cleaning Composition
  申请人：RECKITT BENCKISER (BRANDS) LIMITED

  公开号：US20160298057A1

  公开（公告）日：2016-10-13

  The invention relates to a dishwasher machine cleaning detergent composition that is capable of being used during a normal dishwashing cleaning cycle.