1-O-[[(Z)-3-[[(Z)-5-(hydroxymethoxymethoxy)-3-(hydroxymethoxymethoxycarbonyl)-5-oxopent-2-enoyl]oxymethoxymethoxycarbonyl]-5-[[(Z)-5-[[(Z)-3-[[(Z)-5-(hydroxymethoxymethoxy)-3-(hydroxymethoxymethoxycarbonyl)-5-oxopent-2-enoyl]oxymethoxymethoxycarbonyl]-5-[[(Z)-5-(hydroxymethoxymethoxy)-3-(hydroxymethoxymethoxycarbonyl)-5-oxopent-2-enoyl]peroxymethoxy]-5-oxopent-2-enoyl]oxymethoxymethoxy]-3-[[(Z)-3-[[(Z)-5-(hydroxymethoxymethoxy)-3-(hydroxymethoxymethoxycarbonyl)-5-oxopent-2-enoyl]oxymethoxymethoxycarbonyl]-5-[[(Z)-5-(hydroxymethoxymethoxy)-3-(hydroxymethoxymethoxycarbonyl)-5-oxopent-2-enoyl]peroxymethoxy]-5-oxopent-2-enoyl]oxymethoxymethoxycarbonyl]-5-oxopent-3-enoyl]oxymethoxymethoxy]-5-oxopent-3-enoyl]oxymethoxymethyl] 2-O,3-O-bis(hydroxymethoxymethyl) (Z)-prop-1-ene-1,2,3-tricarboxylate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1-O-[[(Z)-3-[[(Z)-5-(hydroxymethoxymethoxy)-3-(hydroxymethoxymethoxycarbonyl)-5-oxopent-2-enoyl]oxymethoxymethoxycarbonyl]-5-[[(Z)-5-[[(Z)-3-[[(Z)-5-(hydroxymethoxymethoxy)-3-(hydroxymethoxymethoxycarbonyl)-5-oxopent-2-enoyl]oxymethoxymethoxycarbonyl]-5-[[(Z)-5-(hydroxymethoxymethoxy)-3-(hydroxymethoxymethoxycarbonyl)-5-oxopent-2-enoyl]peroxymethoxy]-5-oxopent-2-enoyl]oxymethoxymethoxy]-3-[[(Z)-3-[[(Z)-5-(hydroxymethoxymethoxy)-3-(hydroxymethoxymethoxycarbonyl)-5-oxopent-2-enoyl]oxymethoxymethoxycarbonyl]-5-[[(Z)-5-(hydroxymethoxymethoxy)-3-(hydroxymethoxymethoxycarbonyl)-5-oxopent-2-enoyl]peroxymethoxy]-5-oxopent-2-enoyl]oxymethoxymethoxycarbonyl]-5-oxopent-3-enoyl]oxymethoxymethoxy]-5-oxopent-3-enoyl]oxymethoxymethyl] 2-O,3-O-bis(hydroxymethoxymethyl) (Z)-prop-1-ene-1,2,3-tricarboxylate
• 化学式: C₁₀₀H₁₂₂O₉₃
• 分子量: 2812.0
• InChiKey: XWSQZEORQMLXSL-SMONVLDJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -9
• 重原子数：
  193
• 可旋转键数：
  140
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  1230
• 氢给体数：
  12
• 氢受体数：
  93

文献信息

• Dendrimers and Dendrimer Applications
  申请人：Pandit Abhay

  公开号：US20110217750A1

  公开（公告）日：2011-09-08

  An activatable functionalised N th generation dendrimer having: a core comprising a first monomer having at least two carboxylic acid functional groups; and N successive generations, where N=0 to 10, wherein each generation comprises: a second monomer having at least two alcohol functional groups, wherein at least one alcohol group is bonded to a carboxylic acid group of the first monomer of the prior generation, and an additional first monomer attached to a second alcohol function group of said second monomer of that generation; and the final generation having attached thereto at said second alcohol functional group of said second monomer, a moiety having a dicarboxylic acid functional group, activatable by treatment with a carboxylic acid activating reagent such that reactivity of the carboxylic acid functional group is increased. The dendrimer, when activated, may be used in applications such as polymer crosslinking and/or nanoshell production.

  一种可激活的功能化第N代树状分子，包括：核心包括至少两个羧酸官能团的第一单体；和N代连续的代数，其中N = 0到10，其中每一代包括：至少两个醇官能团的第二单体，其中至少一个醇基与前一代的第一单体的羧酸基团结合，以及附加到该代的第二单体的第二醇官能团的另一个第一单体；最终一代附着在该第二单体的第二醇官能团上的一个具有二羧酸官能团的基团，通过与羧酸活化试剂处理而激活，从而增加羧酸官能团的反应性。激活后的树状分子可用于聚合物交联和/或纳米壳制备等应用。
• US8734870B2
  申请人：——

  公开号：US8734870B2

  公开（公告）日：2014-05-27
• [EN] DIHYDROPYRIMIDONE MULTIMERS AND THEIR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS<br/>[FR] MULTIMÈRES DIHYDROPYRIMIDONE ET LEUR UTILISATION EN TANT QU'INHIBITEURS DE L'ÉLASTASE NEUTROPHILE HUMAINE
  申请人：ARGENTA DISCOVERY LTD

  公开号：WO2006136857A1

  公开（公告）日：2006-12-28

  [EN] A compound of formula M-L-M (I) wherein L is a linker and each M is independently a group of formula (II) is useful in therapy, e.g. of respiratory diseases.
  [FR] L'invention concerne un composé de formule M-L-M (I), où L est un liant et chaque M est indépendamment un groupe de formule (II), utile pour le traitement, par exemple, de maladies respiratoires.