2-(2,5-dioxo-3-pentan-2-ylsulfanylpyrrolidin-1-yl)-N-methylacetamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-(2,5-dioxo-3-pentan-2-ylsulfanylpyrrolidin-1-yl)-N-methylacetamide
• 化学式: C₁₂H₂₀N₂O₃S
• 分子量: 272.37
• InChiKey: TYJSIDLDVMPXBV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  91.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• ANTIBODY CONJUGATES
  申请人：Ventana Medical Systems, Inc.

  公开号：US20140147906A1

  公开（公告）日：2014-05-29

  Antibody/signal-generating moiety conjugates are disclosed that include an antibody covalently linked to a signal-generating moiety through a heterobifunctional polyalkyleneglycol linker. The disclosed conjugates show exceptional signal-generation in immunohistochemical and in situ hybridization assays on tissue sections and cytology samples. In one embodiment, enzyme-metallographic detection of nucleic acid sequences with hapten-labeled probes can be accomplished using the disclosed conjugates as a primary antibody without amplification.
• US9315789B2
  申请人：——

  公开号：US9315789B2

  公开（公告）日：2016-04-19