(2-Ethyl-5-methylpyrazol-3-yl)methyl methanesulfonate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: (2-Ethyl-5-methylpyrazol-3-yl)methyl methanesulfonate
• 英文别名: (2-ethyl-5-methylpyrazol-3-yl)methyl methanesulfonate
• 化学式: C₈H₁₄N₂O₃S
• 分子量: 218.28
• InChiKey: RCKSMVAWGGVYIE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  69.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• NOVEL SUBSTITUTED INDOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS
  申请人：Minne Garrett Berlond

  公开号：US20140148450A1

  公开（公告）日：2014-05-29

  The present invention is concerned with novel substituted indole derivatives of Formula (I) wherein R 1 , R 2 , R 3 , A 1 , A 2 , A 3 , Y and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
• US9115143B2
  申请人：——

  公开号：US9115143B2

  公开（公告）日：2015-08-25