The present invention provides a special reagent for the pretreatment of sample materials. The pretreatment with the reagent according to the invention enables the isolation of nucleic acids by a uniform method from very diverse sample materials, in particular different bioprocess samples, even if the nucleic acids are only present in small amounts in the sample materials. The reagent used for the pretreatment comprises, as key component, at least one compound comprising an amino group. The invention further relates to methods of purification of nucleic acids, in which the sample material is pretreated correspondingly, and suitable kits.
本发明提供了一种用于样品材料预处理的特殊试剂。使用本发明的试剂进行预处理后,即使
核酸只少量存在于样品材料中,也能通过统一的方法从多种样品材料,特别是不同的
生物工艺样品中分离出
核酸。用于预处理的试剂作为关键成分,至少包括一种含有
氨基的化合物。本发明还涉及
核酸的纯化方法,其中对样品材料进行了相应的预处理,并涉及合适的试剂盒。