2-[2-(Azete-2-carbonyl)hydrazinyl]ethanesulfonic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 2-[2-(Azete-2-carbonyl)hydrazinyl]ethanesulfonic acid
• 英文别名: 2-[2-(azete-2-carbonyl)hydrazinyl]ethanesulfonic acid
• 化学式: C₆H₉N₃O₄S
• 分子量: 219.22
• InChiKey: CKEKZQVOAQVJAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.3
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  116
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• ASSESSMENT OF RISK OF HYPERTENSION AND METHODS BASED THEREON
  申请人：Westfälische Wilhelms-Universität Münster

  公开号：EP2926132A1

  公开（公告）日：2015-10-07
• [EN] ASSESSMENT OF RISK OF HYPERTENSION AND METHODS BASED THEREON<br/>[FR] ÉVALUATION DU RISQUE D'HYPERTENSION ET MÉTHODES BASÉES SUR CELLE-CI
  申请人：UNIV MUENSTER WILHELMS

  公开号：WO2014082990A1

  公开（公告）日：2014-06-05

  Provided is a method of analysing whether the blood pressure of a subject is sensitive to sodium intake and/or of assessing the susceptibility of a subject to develop hypertension. In the method erythrocytes of the subject are suspended in two sodium chloride solutions of about physiological osmolality. The sodium chloride concentration of one of the two solutions is at least about 25 mM lower than in the other solution. After allowing the suspended erythrocytes in the two sodium chloride solutions to settle for a period of time sufficient to allow the formation of a supernatant the difference in height of the supernatant between the two sodium chloride solutions is detected. An increased difference in height of the supematants, relative to a threshold value, indicates that the subject's blood pressure is sensitive to sodium intake and/or that the subject is susceptible to develop hypertension.