(2,5-Dioxopyrrolidin-1-yl) 4-[3-[3-[3-[[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutanoyl]amino]propoxy]-2,2-bis[3-[[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutanoyl]amino]propoxymethyl]propoxy]propylamino]-4-oxobutanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2,5-Dioxopyrrolidin-1-yl) 4-[3-[3-[3-[[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutanoyl]amino]propoxy]-2,2-bis[3-[[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutanoyl]amino]propoxymethyl]propoxy]propylamino]-4-oxobutanoate
• 英文别名: (2,5-dioxopyrrolidin-1-yl) 4-[3-[3-[3-[[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutanoyl]amino]propoxy]-2,2-bis[3-[[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutanoyl]amino]propoxymethyl]propoxy]propylamino]-4-oxobutanoate
• 化学式: C₄₉H₆₈N₈O₂₄
• 分子量: 1153.1
• InChiKey: KDECCAQOEPMIOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -6.1
• 重原子数：
  81
• 可旋转键数：
  44
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  408
• 氢给体数：
  4
• 氢受体数：
  24

文献信息

• Peptide-based multimeric targeted contrast agents
  申请人：Zhang Zhaoda

  公开号：US20060039861A1

  公开（公告）日：2006-02-23

  Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.

  本文描述了肽和肽靶向多聚对比剂，以及制备和使用对比剂的方法。
• Method of Relieving, Improving, Preventing or Treating Xerostomia
  申请人：SUNBIO INC.

  公开号：US20140155457A1

  公开（公告）日：2014-06-05

  Provided is a method of relieving, improving, preventing or treating xerostomia including applying an oral cavity composition including a polyethylene glycol (PEG) derivative whose reactor is modified to form a covalent bond with an epithelial cell of the oral cavity. An oral moisturizing effect and moisture persistency are increased and the method is effective against xerostomia due to aging or disease.