(1-Hydroxy-2,2,5,5-tetramethylpyrrolidin-3-yl)methyl methanesulfonate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: (1-Hydroxy-2,2,5,5-tetramethylpyrrolidin-3-yl)methyl methanesulfonate
• 英文别名: (1-hydroxy-2,2,5,5-tetramethylpyrrolidin-3-yl)methyl methanesulfonate
• 化学式: C₁₀H₂₁NO₄S
• 分子量: 251.35
• InChiKey: JRRVAYIKWWLORG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  75.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• COMPOSITIONS AND METHODS TO ASSESS THE CAPACITY OF HDL TO SUPPORT REVERSE CHOLESTEROL TRANSPORT
  申请人：Oda Michael N.

  公开号：US20140162376A1

  公开（公告）日：2014-06-12

  The invention provides compositions and methods for assessing the capacity of high density lipoprotein (HDL) to support reverse cholesterol transport in blood by measuring exchange if HDL-specific spin-labeled lipoprotein probes and electron paramagnetic spectroscopy. The invention also provides methods to identify individuals at risk for cardiovascular disease, to monitor the treatment of cardiovascular disease and in the development of therapies to treat cardiovascular disease. The invention also provides methods to identify individuals at risk for Alzheimer's disease, to monitor the treatment of Alzheimer's disease and in the development of therapies to treat Alzheimer's disease.