(2-Aminoacetyl) 3-methylbutanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2-Aminoacetyl) 3-methylbutanoate
• 英文别名: (2-aminoacetyl) 3-methylbutanoate
• 化学式: C₇H₁₃NO₃
• 分子量: 159.18
• InChiKey: FSINYWPNTOBTFB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  69.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• TRIMETHYLAMINE-N-OXIDE AS BIOMARKER FOR THE PREDISPOSITION FOR WEIGHT GAIN AND OBESITY
  申请人：Nestec S.A.

  公开号：EP2929347B1

  公开（公告）日：2017-09-06
• ISOVALERYLGLYCINE AS BIOMARKER FOR THE PREDISPOSITION FOR WEIGHT GAIN AND OBESITY
  申请人：Nestec S.A.

  公开号：EP2929355A1

  公开（公告）日：2015-10-14
• METHOD FOR DIAGNOSING ESTHETIC DEGRADATIONS OF SKIN
  申请人：L'OREAL

  公开号：EP3987064A1

  公开（公告）日：2022-04-27
• [EN] ISOVALERYLGLYCINE AS BIOMARKER FOR THE PREDISPOSITION FOR WEIGHT GAIN AND OBESITY<br/>[FR] ISOVALÉRYLGLYCINE EN TANT QUE BIOMARQUEUR POUR LA PRÉDISPOSITION AU GAIN DE POIDS ET À L'OBÉSITÉ
  申请人：NESTEC SA

  公开号：WO2014086605A1

  公开（公告）日：2014-06-12

  The present invention relates generally to the field of nutrition and health. In particular, the present invention relates to a new biomarker, its use and a method that allows it to diagnose the likelihood to resist diet induced weight gain, and/or to be susceptible to a diet induced weight gain. For example, the biomarker may be isovalerylglycine.
• [EN] METHOD FOR DIAGNOSING ESTHETIC DEGRADATIONS OF SKIN<br/>[FR] PROCÉDÉ DE DIAGNOSTIC DE DÉGRADATIONS ESTHÉTIQUES DE LA PEAU
  申请人：OREAL

  公开号：WO2020260355A1

  公开（公告）日：2020-12-30

  The present invention relates to a method for diagnosing esthetic degradations of skin, in particular linked to pollution, in a subject, comprising a step (a) of determining, in a skin sample of the subject, the level of at least one marker chosen from the group constituted of (i) bacteria of the species Propionibacterim acnes, bacteria of the family Micrococcaceae, bacteria of the genus Brachybacterium, bacteria of the genus Brevibacterium, bacteria of the order Burkholderiales, bacteria of the genus Parococcus, bacteria of the family Rhodobacteraceae and bacteria of the genus Fusobacterium, and (ii) metabolites of these bacteria chosen from 3-hydroxy-3-methylglutarate, 3-methylglutarate/2-methylglutarate, 4- guanidinobutanoate, 4-imidazoleacetate, 5-oxoproline, aconitrate, adipate, alanine, alpha- cetoglutarate, arabonate/xylonate, azelate, beta-citrylglutamate, choline, cis-urocanate, citraconate/gIutaconate, fructose, fumarate, gamma-glutamylalanine, gamma- glutamylglutamine, gamma-glutamylglycine, gamma-glutamylisoleucine, gamma- glutamylleucine, gamma-glutamylserine, gamma-glutamylthreonine, gamma- glutamyltryptophane, gamma-glutamylvaline, glutarate, glycerate, glycerol-3-phosphate, glycine, isovalerylglycine, kynurenate, lactate, linoleoyl ethanolamide, malate, maleate, malonate, maltose, methionine sulfoxide, methylsuccinate, N-acetylalanine, N- acetylarginine, N-acetylaspartate, N-acetylglycine, N-acetylhistidine, N- acetylphenylalanine, N-acetylthreonine, N-acetylvaline, oleamide, ornithine, palmitamide, pimelate, proline, salicylate, sebacate, serine, su be rate, succinate, undecanedioate and S- amino-omega caprolactam.