5-甲基-3,4-己二烯-1-基胺 | 144347-94-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 5-甲基-3,4-己二烯-1-基胺
• 英文名称: 5-Methyl-3,4-hexadien-1-ylamine
• CAS: 144347-94-4
• 化学式: C₇H₁₃N
• 分子量: 111.187
• InChiKey: CGFBTVGYGCDTKL-UHFFFAOYSA-N

物化性质

• 沸点：
  160.2±10.0 °C(Predicted)
• 密度：
  0.795±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  5-甲基-3,4-己二烯-1-基胺 在 4-二甲氨基吡啶 、 potassium carbonate 、 三乙胺 、 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 二氯甲烷 、 丙酮 为溶剂， 生成 2-hydroxy-2-methyl-1-[2-(4-methylphenyl)sulfonyl-1,2-oxazolidin-5-yl]propan-1-one
  参考文献：
  名称：

  烯丙基磺酰胺与二甲基二环氧乙烷的氧化环化反应

  摘要：

  烯丙胺衍生物的二甲基二环氧乙烷烷氧化得到高度官能化的氮杂环，该杂环衍生自中间烯丙基单环氧和二环氧的环化。

  DOI：

  10.1016/s0040-4039(00)77158-9
• 作为产物：
  描述：

  2-methyl-6-(p-toluenesulfonyloxy)-2,3-hexadiene 在 lithium aluminium tetrahydride 、 sodium azide 作用下， 以 乙醚 、 N,N-二甲基甲酰胺 为溶剂， 生成 5-甲基-3,4-己二烯-1-基胺
  参考文献：
  名称：

  Dimethyldioxirane oxidation of primary amines

  摘要：

  Several primary amines 2 have been oxidized with dimethyldioxirane (1) under a variety of conditions. Mixtures of dimeric nitrosoalkanes 4 and oximes 5 were typically obtained with solutions of the oxidant in excess. In several instances, nitrones 12 were found as byproducts in these reactions. In situ oxidations using oxone in buffered aqueous acetone solution also gave nitrosoalkanes 4 and oximes 3 as important products; in addition, oxaziridines 11 were obtained in significant amounts in biphasic procedures containing methylene chloride. The corresponding nitroalkanes 3 were not formed in major amounts in either oxidation procedure, unless large excesses of oxidant were used. These results are discussed in terms of the several competing processes which occur under the different reaction conditions.

  DOI：

  10.1021/jo00051a017

文献信息

• Crandall Jack K., Reix Thierry, Tetrahedron Lett, 35 (1994) N 16, S 2513-2516
  作者：Crandall Jack K., Reix Thierry

  DOI：——

  日期：——
• Dimethyldioxirane oxidation of primary amines
  作者：Jack K. Crandall、Thierry Reix

  DOI：10.1021/jo00051a017

  日期：1992.12

  Several primary amines 2 have been oxidized with dimethyldioxirane (1) under a variety of conditions. Mixtures of dimeric nitrosoalkanes 4 and oximes 5 were typically obtained with solutions of the oxidant in excess. In several instances, nitrones 12 were found as byproducts in these reactions. In situ oxidations using oxone in buffered aqueous acetone solution also gave nitrosoalkanes 4 and oximes 3 as important products; in addition, oxaziridines 11 were obtained in significant amounts in biphasic procedures containing methylene chloride. The corresponding nitroalkanes 3 were not formed in major amounts in either oxidation procedure, unless large excesses of oxidant were used. These results are discussed in terms of the several competing processes which occur under the different reaction conditions.
• Oxidative cyclizations of allenic sulfonamides with dimethyldioxirane
  作者：Jack K. Crandall、Thierry Reix

  DOI：10.1016/s0040-4039(00)77158-9

  日期：1994.4

  The dimethyldioxirane oxidations of allenic amine derivatives give highly functionalized nitrogen heterocycles derived from cyclizations of intermediate allene mono- and diepoxides.

  烯丙胺衍生物的二甲基二环氧乙烷烷氧化得到高度官能化的氮杂环，该杂环衍生自中间烯丙基单环氧和二环氧的环化。