Prop-2-enyl 4-bromo-5-(dimethylamino)-2,2-dimethyl-5-oxopentanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Prop-2-enyl 4-bromo-5-(dimethylamino)-2,2-dimethyl-5-oxopentanoate
• 英文别名: prop-2-enyl 4-bromo-5-(dimethylamino)-2,2-dimethyl-5-oxopentanoate
• 化学式: C₁₂H₂₀BrNO₃
• 分子量: 306.2
• InChiKey: CHURSAPPZLEJSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• AMPHIPHILIC SILOXANE-CONTAINING VINYLIC MONOMERS AND USES THEREOF
  申请人：Novartis AG

  公开号：US20140171542A1

  公开（公告）日：2014-06-19

  The invention provides an amphiphilic siloxane-containing vinylic monomer which comprises one sole ethylenically unsaturated group and a siloxane-containing group covalently linked to the ethylenically-unsaturated group through a hydrophilic linker. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from an amphiphilic siloxane-containing vinylic monomer of the invention. In addition, the invention provides a method for making silicone hydrogel contact lenses using a water-based lens-forming formulation comprising an amphiphilic siloxane-containing vinylic monomer of the invention and/or an actinically-crosslinkable silicone-containing prepolymer of the invention.
• US9103965B2
  申请人：——

  公开号：US9103965B2

  公开（公告）日：2015-08-11
• US9541676B2
  申请人：——

  公开号：US9541676B2

  公开（公告）日：2017-01-10